SCHEMBL182244

SCHEMBL182244

C=C(C)C(=O)NCCCN(C(C)C)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
TGFBR1 P36897 1/20 0.37
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
HPGD P15428 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
RXFP1 Q9HBX9 1/20 0.31
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
DNM1 Q05193 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28197375 0.95 KDM4E (0.36) KDM4ETGFBR1ALDH1A1MAPK1HIF1A
SCHEMBL4820203 0.89 ACHE (0.39) KDM4ETGFBR1ALDH1A1SIGMAR1BCHE
SCHEMBL16908423 0.81 KDM4E (0.41) KDM4ETGFBR1ALDH1A1MAPK1HIF1A
SCHEMBL21954 0.79 KDM4E (0.56) KDM4EALDH1A1HPGDLMNAMEN1
SCHEMBL182277 0.79 KDM4E (0.39) KDM4EALDH1A1HPGDRXFP1LMNA
SCHEMBL5444884 0.78 ALDH1A1 (0.46) KDM4EALDH1A1MAPK1LMNAMEN1
SCHEMBL632876 0.78 KDM4E (0.46) KDM4ETGFBR1ALDH1A1MAPK1HIF1A
SCHEMBL907569 0.78 KDM4E (0.52) KDM4ETGFBR1ALDH1A1MAPK1HIF1A
Ammonia Solution, Strong SCHEMBL23532663 0.78 KDM4E (0.54) KDM4EALDH1A1HPGDLMNAMEN1
SCHEMBL18331597 0.78 KDM4E (0.42) KDM4EMAPK1HIF1ASIGMAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011127364-A2 A COMBINATION OF CROSSLINKED CATIONIC AND AMPHOLYTIC POLYMERS FOR PERSONAL AND HOUSEHOLD APPLICATIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2011-10-13 WO claimed
EP-0123140-B1 BINDER FOR CATIONICALLY ELECTRODEPOSITABLE COATING BASF Lacke + Farben AG (DE) 1986-07-23 EP claimed
EP-2039340-B2 SKIN CLEANSING COMPOSITION KAO CORP (JP) 2020-04-01 EP disclosed
EP-2039340-B1 SKIN CLEANSING COMPOSITION KAO CORP (JP) 2017-04-26 EP disclosed
US-9159992-B2 Negative electrode active material for lithium ion secondary battery and lithium ion secondary battery ZEON CORPORATION (JP) 2015-10-13 US disclosed
EP-2370531-B1 WATER-BASED INK FOR INK-JET PRINTING KAO CORP (JP) 2014-08-20 EP disclosed
US-8680174-B2 Water-based ink for ink-jet printing KAO CORPORATION (JP) 2014-03-25 US disclosed
EP-2684926-A1 SHATTERPROOFING MEMBER WITH HARDENABLE PRESSURE-SENSITIVE ADHESIVE LAYER Nitto Denko Corporation (JP) 2014-01-15 EP disclosed
US-20140004331-A1 SHATTERPROOFING MEMBER WITH HARDENABLE PRESSURE-SENSITIVE ADHESIVE LAYER NITTO DENKO CORPORATION (JP) 2014-01-02 US disclosed
EP-2631067-A1 HIGHLY FLAME-RETARDANT POLYMER MEMBER, FLAME-RETARDANT ARTICLE, AND FLAME-RETARDING METHOD Nitto Denko Corporation (JP) 2013-08-28 EP disclosed
US-20130189516-A1 FLAME-RETARDANT POLYMER MEMBER WITH ENVIRONMENTAL RESISTANCE AND FLAME-RETARDANT POLYMER MEMBER WITH HYGIENIC PROPERTY NITTO DENKO CORPORATION (JP) 2013-07-25 US disclosed
US-20100273016-A1 SURFACE TREATMENT AGENT FOR PAPER KAO CORPORATION (JP) 2010-10-28 US disclosed
EP-2199463-A1 SURFACE TREATMENT AGENT FOR PAPER Kao Corporation (JP) 2010-06-23 EP disclosed
US-20090286707-A1 SKIN CLEANSING COMPOSITION KAO CORPORATION (JP) 2009-11-19 US disclosed
US-20090253603-A1 CLEANSING COMPOSITION KAO CORPORATION (JP) 2009-10-08 US disclosed
EP-2039340-A1 SKIN CLEANSING COMPOSITION Kao Corporation (JP) 2009-03-25 EP disclosed
EP-2039751-A1 CLEANSING COMPOSITION Kao Corporation (JP) 2009-03-25 EP disclosed
US-20090054291-A1 Soil Releasing Agent for Fiber KAO CORPORATION (JP) 2009-02-26 US disclosed
US-7407706-B2 Encapsulated matter comprising multiple polymeric coatings of opposite charges and production process thereof SEIKO EPSON CORPORATION (JP) 2008-08-05 US disclosed
US-20060222851-A1 Encapsulated matter and production process thereof SEIKO EPSON CORPORATION 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090253603-A1 CLEANSING COMPOSITION SGMS1, SGMS2, DEGS1 KDM4E 2370/4885TGFBR1 4412/4885ALDH1A1 4392/4885
US-20090286707-A1 SKIN CLEANSING COMPOSITION DEGS1, SGMS1, SPTAN1 KDM4E 2007/4885TGFBR1 3027/4885ALDH1A1 3740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.