SCHEMBL182277

SCHEMBL182277

C=C(C)C(=O)NCCCN(CC(C)C)CC(C)C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
TP53 P04637 3/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
GAA P10253 1/20 0.33
ANPEP P15144 2/20 0.33
RNPEP Q9H4A4 2/20 0.33
DNPEP Q9ULA0 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16908423 0.86 KDM4E (0.41) KDM4EMEN1KMT2AALDH1A1GAA
SCHEMBL5444884 0.82 ALDH1A1 (0.46) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL93199 0.81 ALDH1A1 (0.51) KDM4EMEN1KMT2AALDH1A1GAA
SCHEMBL1547624 0.81 KDM4E (0.38) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL25557372 0.80 ANPEP (0.41) KDM4EALDH1A1GAAANPEPRNPEP
SCHEMBL21954 0.80 KDM4E (0.56) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL182532 0.79 DRD2 (0.41) KDM4EALDH1A1HPGDGAA
SCHEMBL135640 0.79 DNM1 (0.40) KDM4EALDH1A1GAACA12CA1
Hydrochloric Acid SCHEMBL10636930 0.79 ALDH1A1 (0.50) KDM4EMEN1KMT2AALDH1A1GAA
SCHEMBL182244 0.79 KDM4E (0.37) KDM4EMEN1KMT2ARXFP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2039340-B2 SKIN CLEANSING COMPOSITION KAO CORP (JP) 2020-04-01 EP disclosed
EP-2039340-B1 SKIN CLEANSING COMPOSITION KAO CORP (JP) 2017-04-26 EP disclosed
US-9159992-B2 Negative electrode active material for lithium ion secondary battery and lithium ion secondary battery ZEON CORPORATION (JP) 2015-10-13 US disclosed
EP-2370531-B1 WATER-BASED INK FOR INK-JET PRINTING KAO CORP (JP) 2014-08-20 EP disclosed
US-8680174-B2 Water-based ink for ink-jet printing KAO CORPORATION (JP) 2014-03-25 US disclosed
EP-2684926-A1 SHATTERPROOFING MEMBER WITH HARDENABLE PRESSURE-SENSITIVE ADHESIVE LAYER Nitto Denko Corporation (JP) 2014-01-15 EP disclosed
US-20140004331-A1 SHATTERPROOFING MEMBER WITH HARDENABLE PRESSURE-SENSITIVE ADHESIVE LAYER NITTO DENKO CORPORATION (JP) 2014-01-02 US disclosed
EP-2631067-A1 HIGHLY FLAME-RETARDANT POLYMER MEMBER, FLAME-RETARDANT ARTICLE, AND FLAME-RETARDING METHOD Nitto Denko Corporation (JP) 2013-08-28 EP disclosed
US-20130210303-A1 HIGHLY FLAME-RETARDANT POLYMER MEMBER, FLAME-RETARDANT ARTICLE, AND FLAME-RETARDING METHOD NITTO DENKO CORPORATION (JP) 2013-08-15 US disclosed
US-20130189516-A1 FLAME-RETARDANT POLYMER MEMBER WITH ENVIRONMENTAL RESISTANCE AND FLAME-RETARDANT POLYMER MEMBER WITH HYGIENIC PROPERTY NITTO DENKO CORPORATION (JP) 2013-07-25 US disclosed
US-8048394-B2 Mesoporous silica particles KAO CORPORATION (JP) 2011-11-01 US disclosed
US-7964545-B2 Skin cleansing composition KAO CORPORATION (JP) 2011-06-21 US disclosed
US-7960327-B2 Cleansing composition KAO CORPORATION (JP) 2011-06-14 US disclosed
US-20100273016-A1 SURFACE TREATMENT AGENT FOR PAPER KAO CORPORATION (JP) 2010-10-28 US disclosed
EP-2199463-A1 SURFACE TREATMENT AGENT FOR PAPER Kao Corporation (JP) 2010-06-23 EP disclosed
US-20090286707-A1 SKIN CLEANSING COMPOSITION KAO CORPORATION (JP) 2009-11-19 US disclosed
US-20090253603-A1 CLEANSING COMPOSITION KAO CORPORATION (JP) 2009-10-08 US disclosed
EP-2039340-A1 SKIN CLEANSING COMPOSITION Kao Corporation (JP) 2009-03-25 EP disclosed
EP-2039751-A1 CLEANSING COMPOSITION Kao Corporation (JP) 2009-03-25 EP disclosed
US-20090054291-A1 Soil Releasing Agent for Fiber KAO CORPORATION (JP) 2009-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090253603-A1 CLEANSING COMPOSITION SGMS1, SGMS2, DEGS1 KDM4E 2370/4885TP53 4568/4885MEN1 3913/4885
US-20090286707-A1 SKIN CLEANSING COMPOSITION DEGS1, SGMS1, SPTAN1 KDM4E 2007/4885TP53 4404/4885MEN1 3547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.