Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230378 | 0.81 | MPL (0.49) | STAT3MCHR1TRPV1MPL | |
| SCHEMBL18230481 | 0.78 | STAT3 (0.47) | STAT3MCHR1TRPV1 | |
| SCHEMBL18230521 | 0.73 | TRPV1 (0.59) | STAT3TRPV1 | |
| SCHEMBL26606541 | 0.73 | SCD (0.65) | — | |
| SCHEMBL30576758 | 0.73 | SCD (0.65) | — | |
| SCHEMBL18230388 | 0.73 | LRRK2 (0.61) | STAT3BTK | |
| SCHEMBL18230428 | 0.71 | MAPT (0.46) | STAT3TRPV1WNT3A | |
| SCHEMBL18230368 | 0.71 | TRPV4 (0.46) | STAT3TRPV1 | |
| SCHEMBL18094493 | 0.70 | MCHR1 (0.41) | STAT3MCHR1TRPV1MPLBTK | |
| SCHEMBL1472528 | 0.69 | HTR2C (0.69) | P2RY14ALOX5APFEN1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |