SCHEMBL18239238

SCHEMBL18239238

C#CC[S+]([O-])Cc1ccc(Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.41
MAOB P27338 2/20 0.36
IDO1 P14902 3/20 0.35
SLC6A4 P31645 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A3 Q01959 2/20 0.34
HTR2A P28223 1/20 0.34
HRH1 P35367 1/20 0.34
HTR2B P41595 1/20 0.34
CHRNA4 P43681 1/20 0.34
TAAR1 Q96RJ0 2/20 0.33
AGXT P21549 2/20 0.32
MIF P14174 1/20 0.32
LMNA P02545 2/20 0.31
CYP2A6 P11509 1/20 0.31
MAOA P21397 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196856 0.81 IDO1 (0.46) MAOBIDO1SLC6A4SLC6A2SLC6A3
SCHEMBL18239234 0.77 PYCR1 (0.46) PYCR1MAOBIDO1SLC6A4TAAR1
SCHEMBL4341805 0.71 MAOB (0.47) MAOBIDO1AGXTMAOA
SCHEMBL19649630 0.69 IDO1 (0.42) PYCR1MAOBIDO1SLC6A4SLC6A2
SCHEMBL19385816 0.68 MEN1 (0.40) TAAR1MIFLMNA
SCHEMBL9625907 0.68 IDO1 (0.34) MAOBIDO1SLC6A4SLC6A2SLC6A3
SCHEMBL1921131 0.68 PYCR1 (0.50) PYCR1MAOBIDO1SLC6A4SLC6A2
SCHEMBL828064 0.67 AOC3 (0.42) SLC6A4
SCHEMBL30958874 0.67 SIGMAR1 (0.41) IDO1TAAR1LMNA
SCHEMBL9490107 0.67 IDO1 (0.50) MAOBIDO1SLC6A4SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11053175-B2 Thioether compounds as nitrification inhibitors BASF SE (DE) 2021-07-06 US disclosed
US-20180134633-A1 THIOETHER COMPOUNDS AS NITRIFICATION INHIBITORS BASF SE (DE) 2018-05-17 US disclosed
US-20180134633-A1 THIOETHER COMPOUNDS AS NITRIFICATION INHIBITORS BASF SE (DE) 2018-05-17 US disclosed
WO-2016180859-A1 THIOETHER COMPOUNDS AS NITRIFICATION INHIBITORS BASF SE (DE) 2016-11-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11053175-B2 Thioether compounds as nitrification inhibitors TST, NOS1, NAT1 PYCR1 1525/4885MAOB 1556/4885IDO1 886/4885
US-20180134633-A1 THIOETHER COMPOUNDS AS NITRIFICATION INHIBITORS TST, NOS1, NAT1 PYCR1 1525/4885MAOB 1556/4885IDO1 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.