Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249389 | 0.82 | ALDH1A1 (0.36) | PRKCACA12CA1CA2CA9 | |
| SCHEMBL12516496 | 0.78 | ALDH1A1 (0.39) | CA12CA1CA2CA9CHRNB2 | |
| SCHEMBL25199135 | 0.74 | MMP1 (0.46) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL18249490 | 0.74 | CHRNB2 (0.36) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL18249444 | 0.71 | UTS2R (0.46) | PRKCA | |
| SCHEMBL24439478 | 0.71 | CHRNB2 (0.46) | CA12CA1CA2CA9CHRNB2 | |
| SCHEMBL18249404 | 0.70 | CYP4F2 (0.40) | PRKCACA12CA1CA2CA9 | |
| SCHEMBL20164268 | 0.68 | MMP1 (0.37) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL254845 | 0.68 | CA12 (0.36) | CA12CA1CA2CA9CHRNB2 | |
| SCHEMBL14763891 | 0.67 | MMP1 (0.48) | MMP1MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016184884-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-11-24 | — | — | WO | disclosed |