Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423439 | 0.65 | CYP3A4 (0.38) | — | |
| SCHEMBL12541553 | 0.61 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBGAANPSR1 | |
| SCHEMBL43657 | 0.61 | KDM4E (0.41) | ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL12310076 | 0.61 | ALDH1A1 (0.36) | ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL11529888 | 0.59 | NPC1 (0.38) | ALDH1A1KDM4EPOLB | |
| SCHEMBL17789200 | 0.59 | ALDH1A1 (0.44) | ALDH1A1KDM4EPOLBGAANPSR1 | |
| SCHEMBL6675514 | 0.57 | CA12 (0.65) | ALDH1A1KDM4EPOLBGAANPSR1 | |
| SCHEMBL9550360 | 0.56 | ALDH1A1 (0.32) | ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL22899093 | 0.56 | ADORA2B (0.31) | — | |
| SCHEMBL13259498 | 0.56 | ALDH1A1 (0.41) | ALDH1A1KDM4EPOLBGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160355616-A1 | Polyvinyl Pyrrolidone analog Polymers | LOGIN ROBERT BERNARD (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160355616-A1 | Polyvinyl Pyrrolidone analog Polymers | LOGIN ROBERT BERNARD (US) | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160355616-A1 | Polyvinyl Pyrrolidone analog Polymers | PBRM1, HMBS, BPGM | ALDH1A1 1117/4885KDM4E 2360/4885POLB 817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.