Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.41 |
| ▸ | GPR4 | P46093 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291271 | 0.83 | CDK4 (0.41) | CDK4CDK6GPR4KCNH2GABRA1 | |
| SCHEMBL20038452 | 0.83 | CDK4 (0.41) | CDK4CDK6GPR4KCNH2SMN1; SMN2 | |
| SCHEMBL20037443 | 0.82 | CDK4 (0.50) | CDK4CDK6GPR4KCNH2SMN1; SMN2 | |
| SCHEMBL20249148 | 0.82 | CDK4 (0.40) | CDK4CDK6PRMT5WDR77GPR4 | |
| SCHEMBL13853395 | 0.79 | L3MBTL1 (0.53) | CHRM1PRMT5WDR77KCNH2GABRA1 | |
| SCHEMBL14993193 | 0.78 | ALDH1A1 (0.53) | CDK4CDK6 | |
| SCHEMBL18291282 | 0.78 | CHRNB2 (0.41) | — | |
| SCHEMBL24648953 | 0.77 | MGLL (0.43) | GPR4KCNH2SMN1; SMN2 | |
| SCHEMBL14307263 | 0.77 | CXCR4 (0.53) | CHRM1 | |
| Hydrochloric Acid SCHEMBL1306753 | 0.77 | ALDH1A1 (0.52) | CDK4CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016194831-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | 帝人ファーマ株式会社 | 2016-12-08 | — | — | WO | disclosed |