Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.46 |
| ▸ | CCND1 | P24385 | 3/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29915749 | 0.93 | ALDH1A1 (0.43) | CDK4CCND1PLGPLAULNPEP | |
| SCHEMBL111621 | 0.93 | ALDH1A1 (0.43) | CDK4CCND1PLGPLAULNPEP | |
| SCHEMBL108285 | 0.86 | HTR2A (0.42) | CDK4CCND1PLGPLAUTNF | |
| SCHEMBL29670034 | 0.86 | HTR2A (0.42) | CDK4CCND1PLGPLAUTNF | |
| SCHEMBL18307589 | 0.86 | CDK4 (0.52) | CDK4CCND1PLGPLAULNPEP | |
| Quinoline SCHEMBL27933335 | 0.84 | CDK4 (0.43) | CDK4CCND1LNPEPTLR8KDM4E | |
| SCHEMBL3919143 | 0.83 | MEN1 (0.54) | CDK4CCND1PLGPLAUSPHK2 | |
| SCHEMBL6941609 | 0.82 | HTR2A (0.40) | CDK4CCND1PLGPLAUTNF | |
| SCHEMBL29803617 | 0.79 | GPR35 (0.42) | TNFHTR2AHTR2CKDM4EMEN1 | |
| SCHEMBL108725 | 0.79 | GPR35 (0.42) | TNFHTR2AHTR2CKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103517703-B | Stain and application thereof | 天野酶制品株式会社 | 2016-11-09 | — | — | CN | claimed |
| EP-2623093-B1 | DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES | AMANO ENZYME INC (JP) | 2016-05-25 | — | — | EP | claimed |
| CN-103998016-B | Employ the dyeing of the keratin fiber of indole analog | AMANO ENZYME INC. (JP) | 2015-09-16 | — | — | CN | claimed |
| US-20140359950-A1 | DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE | AMANO ENZYME INC. (JP) | 2014-12-11 | — | — | US | claimed |
| EP-2708223-B1 | DYEING AGENT AND USE FOR SAME | AMANO ENZYME INC (JP) | 2017-02-01 | — | — | EP | disclosed |
| CN-103517703-B | Stain and application thereof | 天野酶制品株式会社 | 2016-11-09 | — | — | CN | disclosed |
| EP-3067041-A1 | METHOD FOR DYEING KERATIN FIBERS, KERATIN FIBER DYE | Shisei Chemical Co., Ltd. (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-9358198-B2 | Dyeing of keratin fibers using indole analogue | AMANO ENZYME INC. (JP) | 2016-06-07 | — | — | US | disclosed |
| EP-2623093-B1 | DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES | AMANO ENZYME INC (JP) | 2016-05-25 | — | — | EP | disclosed |
| CN-103998016-B | Employ the dyeing of the keratin fiber of indole analog | AMANO ENZYME INC. (JP) | 2015-09-16 | — | — | CN | disclosed |
| US-20140359950-A1 | DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE | AMANO ENZYME INC. (JP) | 2014-12-11 | — | — | US | disclosed |
| CN-103998016-A | Dye for keratin fibers using indole analogue | AMANO ENZYME INC | 2014-08-20 | — | — | CN | disclosed |
| US-20030106166-A1 | Compositions for dyeing keratinous fiber | LION CORPORATION (JP) | 2003-06-12 | — | — | US | disclosed |
| US-20030074743-A1 | Hair dye composition | LION CORPORATION (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1240890-A1 | HAIR DYE COMPOSITION | Lion Corporation (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1234569-A1 | COMPOSITIONS FOR DYEING HORNY FIBERS | Lion Corporation (JP) | 2002-08-28 | — | — | EP | disclosed |
| EP-1189576-A2 | HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN | Lion Corporation (JP) | 2002-03-27 | — | — | EP | disclosed |
| EP-1142561-A1 | HAIR DYE COMPOSITIONS | Lion Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| EP-1142562-A1 | HAIR DYE COMPOSITIONS | Lion Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001000144-A2 | HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN | LION CORPORATION (JP) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030106166-A1 | Compositions for dyeing keratinous fiber | KRT18, LPO, CKMT1A; CKMT1B | CDK4 2720/4885CCND1 4180/4885PLG 339/4885 |
| US-20030074743-A1 | Hair dye composition | HAAO, GRHPR, CD44 | CDK4 3705/4885CCND1 2934/4885PLG 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.