Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308837 | 0.84 | KMO (0.41) | MAPK1HSD17B10CYP3A4TSHRERN1 | |
| SCHEMBL1772657 | 0.83 | MAOB (0.50) | CALM1FYNMEN1LMNAGAA | |
| SCHEMBL18311417 | 0.80 | MCHR1 (0.47) | MEN1LMNAGAAMAPTHPGD | |
| SCHEMBL3693339 | 0.79 | MAOB (0.67) | ALOX5PTGS1PTGS2FYNMEN1 | |
| SCHEMBL4386820 | 0.77 | MAOB (0.64) | ALOX5PTGS1PTGS2FYNMEN1 | |
| SCHEMBL29260699 | 0.77 | FYN (0.48) | ALOX5PTGS1PTGS2AURKAKDR | |
| Sulfuric Acid SCHEMBL11482267 | 0.77 | PNLIP (0.47) | ALOX5CALM1FYNMEN1GAA | |
| SCHEMBL18411549 | 0.76 | TSHR (0.50) | MEN1LMNAMAPTHPGDMAPK1 | |
| SCHEMBL12477879 | 0.74 | APP (0.61) | ALOX5PTGS1PTGS2FYNMEN1 | |
| SCHEMBL18311383 | 0.74 | ERN1 (0.50) | ALOX5PTGS1PTGS2FYNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225606-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2022-01-18 | — | — | US | disclosed |
| US-20200248078-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2020-08-06 | — | — | US | disclosed |
| EP-3121247-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-10-02 | — | — | EP | disclosed |
| US-20190256777-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | US | disclosed |
| US-10344215-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2019-07-09 | — | — | US | disclosed |
| EP-3121247-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2017-01-25 | — | — | EP | disclosed |
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11225606-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, PLEC, EML4 | ALOX5 2243/4885PTGS1 4631/4885PTGS2 4649/4885 |
| US-10344215-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, PLEC, EML4 | ALOX5 2243/4885PTGS1 4631/4885PTGS2 4649/4885 |
| US-20190256777-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | ALOX5 2243/4885PTGS1 4631/4885PTGS2 4649/4885 |
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | ALOX5 2243/4885PTGS1 4631/4885PTGS2 4649/4885 |
| US-20200248078-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | ALOX5 2243/4885PTGS1 4631/4885PTGS2 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.