Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12303132 | 0.82 | KDM4E (0.60) | TSHRMAPTNPC1RAB9AKDM4E | |
| SCHEMBL18311417 | 0.80 | MCHR1 (0.47) | MAPTALDH1A1HPGDLMNAERN1 | |
| SCHEMBL21003759 | 0.80 | NPC1 (0.56) | TSHRMAPTNPC1RAB9AKDM4E | |
| SCHEMBL8545077 | 0.80 | TSHR (0.53) | TSHRMAPTNPC1RAB9AKDM4E | |
| SCHEMBL18625279 | 0.77 | GSTP1 (0.57) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18308832 | 0.76 | ALOX5 (0.46) | TSHRMAPTHSD17B10HPGDLMNA | |
| SCHEMBL18308837 | 0.76 | KMO (0.41) | TSHRALDH1A1HSD17B10ERN1ABCB1 | |
| SCHEMBL8545841 | 0.76 | MCL1 (0.56) | TSHRMAPTNPC1RAB9AKDM4E | |
| SCHEMBL18411547 | 0.75 | GAA (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1322956 | 0.75 | KDM4E (0.64) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225606-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2022-01-18 | — | — | US | disclosed |
| US-20200248078-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2020-08-06 | — | — | US | disclosed |
| EP-3121247-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-10-02 | — | — | EP | disclosed |
| US-20190256777-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | US | disclosed |
| US-10344215-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2019-07-09 | — | — | US | disclosed |
| EP-3121247-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2017-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11225606-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, PLEC, EML4 | TSHR 4853/4885MAPT 40/4885NPC1 3628/4885 |
| US-10344215-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, PLEC, EML4 | TSHR 4853/4885MAPT 40/4885NPC1 3628/4885 |
| US-20190256777-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | TSHR 4853/4885MAPT 40/4885NPC1 3628/4885 |
| US-20200248078-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | TSHR 4853/4885MAPT 40/4885NPC1 3628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.