Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.50 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26213880 | 0.88 | MEN1 (0.71) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL13428244 | 0.82 | MEN1 (0.75) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL21648601 | 0.81 | MEN1 (0.73) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL14399201 | 0.81 | MEN1 (0.67) | MEN1BLMKMT2ATHRBRECQL | |
| Tetramethylrhodamine SCHEMBL2054818 | 0.80 | MEN1 (0.71) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL13525202 | 0.80 | MEN1 (1.00) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL18638481 | 0.79 | MEN1 (0.67) | MEN1BLMKMT2ATHRBRECQL | |
| Rhodamine Ii SCHEMBL30320900 | 0.79 | MEN1 (0.64) | MEN1BLMKMT2ATHRBRECQL | |
| Rhodamine Ii SCHEMBL12310066 | 0.79 | MEN1 (0.64) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL13311416 | 0.79 | MEN1 (0.61) | MEN1BLMKMT2ATHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160362418-A1 | CARBOXAMIDE-SUBSTITUTED XANTHENE DYES | AUDAX PRIVATE DEBT LLC, AS AGENT | 2016-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362418-A1 | CARBOXAMIDE-SUBSTITUTED XANTHENE DYES | XDH, CYBA, CHAT | MEN1 1588/4885BLM 3107/4885KMT2A 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.