Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831359 | 0.96 | THRB (0.42) | ALDH1A1TSHRTHRBHSD17B10GAA | |
| SCHEMBL5595387 | 0.96 | THRB (0.42) | ALDH1A1TSHRTHRBHSD17B10GAA | |
| SCHEMBL23894805 | 0.90 | THRB (0.48) | ALDH1A1TSHRTHRBHSD17B10GAA | |
| SCHEMBL12297123 | 0.88 | THRB (0.47) | ALDH1A1TSHRTHRBHSD17B10GAA | |
| SCHEMBL15382568 | 0.86 | ALDH1A1 (0.42) | ALDH1A1TSHRTHRBHSD17B10GAA | |
| SCHEMBL16654664 | 0.86 | THRB (0.55) | ALDH1A1TSHRTHRBHSD17B10GAA | |
| SCHEMBL1831770 | 0.86 | CYP4F2 (0.46) | ALDH1A1TSHRTHRBGAAMAPT | |
| SCHEMBL1520965 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBHSD17B10GAA | |
| Di(Hydroxyethyl)Ether SCHEMBL2799781 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRBHSD17B10GAA | |
| SCHEMBL6895196 | 0.84 | THRB (0.53) | ALDH1A1TSHRTHRBHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3542779-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2021-12-01 | — | — | EP | disclosed |
| US-10980713-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-04-20 | — | — | US | disclosed |
| CN-112074263-A | Dental composition | 登士柏希罗纳有限公司 | 2020-12-11 | — | — | CN | disclosed |
| EP-3542779-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2019-09-25 | — | — | EP | disclosed |
| US-20190274930-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2019-09-12 | — | — | US | disclosed |
| WO-2019173656-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2019-09-12 | — | — | WO | disclosed |
| EP-2662729-A1 | Method for preparation of lithographic printing plate | Fujifilm Corporation (JP) | 2013-11-13 | — | — | EP | disclosed |
| US-8198388-B2 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-8198388-B2 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-8198388-B2 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
| EP-1548021-B1 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY DETREY GMBH (DE) | 2007-03-21 | — | — | EP | disclosed |
| US-20060246017-A1 | Polymerizable phosphoric acid ester derivative and a dental composition employing it | DENTSPLY DE TREY GMBH (DE) | 2006-11-02 | — | — | US | disclosed |
| EP-1601679-A2 | A POYMERIZABLE PHOSPHORIC ACID ESTER DERIVATIVE AND A DENTAL COMPOSITION EMPLOYING IT. | DENTSPLY DETREY GmbH (DE) | 2005-12-07 | — | — | EP | disclosed |
| WO-2005063778-A1 | ONE-PART SELF-ETCHING, SELF-PRIMING DENTAL ADHESIVE COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2005-07-14 | — | — | WO | disclosed |
| WO-2004078100-A2 | A POYMERIZABLE PHOSPHORIC ACID ESTER DERIVATIVE AND A DENTAL COMPOSITION EMPLOYING IT. | DENTSPLY DE TREY GMBH (DE) | 2004-09-16 | — | — | WO | disclosed |
| EP-1454911-A1 | A polymerizable phosphoric acid ester derivative and a dental composition employing it | DENTSPLY DETREY GmbH (DE) | 2004-09-08 | — | — | EP | disclosed |
| EP-0738703-B1 | Acrylic acid derivatives, method for preparing the acrylic acid derivatives, and acrylic acid polymers | NIPPON CATALYTIC CHEM IND (JP) | 2002-05-22 | — | — | EP | disclosed |
| US-5834576-A | CROSSLINKING USING AN ACRYLIC ESTER CONTAINING ETHER GROUPS | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0738703-A2 | Acrylic acid derivatives, method for preparing the acrylic acid derivatives, and acrylic acid polymers | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060246017-A1 | Polymerizable phosphoric acid ester derivative and a dental composition employing it | CBR1, HCAR1, OXSR1 | ALDH1A1 2788/4885TSHR 2272/4885THRB 1723/4885 |
| US-20190274930-A1 | DENTAL COMPOSITION | KATNAL2, PUF60, PGLS | ALDH1A1 2727/4885TSHR 4820/4885THRB 4351/4885 |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | CAD, ASIC1, PDAP1 | ALDH1A1 1101/4885TSHR 4720/4885THRB 3469/4885 |
| US-10980713-B2 | Dental composition | KATNAL2, PUF60, PGLS | ALDH1A1 2727/4885TSHR 4820/4885THRB 4351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.