Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18320800 | 0.89 | KDM4E (0.47) | KDM4EKDM4CALDH1A1MEN1KDM6B | |
| SCHEMBL5101954 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTTDP1DHODH | |
| SCHEMBL5101784 | 0.81 | GPR35 (0.49) | KDM4EDHODHALOX15CSNK2A2CSNK2B | |
| SCHEMBL5090085 | 0.81 | CSNK2A2 (0.40) | KDM4EALDH1A1DHODHALOX15CSNK2A2 | |
| SCHEMBL18320716 | 0.78 | DHODH (0.47) | KDM4EKDM4CALDH1A1MEN1KDM6B | |
| SCHEMBL4251041 | 0.78 | KDM4E (0.69) | KDM4EALDH1A1DHODHGAAHTT | |
| SCHEMBL5102002 | 0.78 | ALOX15 (0.66) | KDM4EALDH1A1TDP1L3MBTL1DHODH | |
| SCHEMBL18321242 | 0.78 | KDM4E (0.44) | KDM4EKDM4CALDH1A1MEN1KDM6B | |
| SCHEMBL69125 | 0.77 | KDM4E (0.64) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL29450085 | 0.77 | KDM4E (0.64) | KDM4EALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |