Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 7/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 7/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18320554 | 0.81 | KDM4E (0.44) | CSNK2A2CSNK2BDHODHKDM4EALOX15 | |
| SCHEMBL5101784 | 0.80 | GPR35 (0.49) | CSNK2A2CSNK2BDHODHKDM4EALOX15 | |
| SCHEMBL5101954 | 0.80 | ALDH1A1 (0.46) | CSNK2A2CSNK2BDHODHKDM4EALOX15 | |
| SCHEMBL837668 | 0.77 | ALOX15 (0.58) | DHODHKDM4EALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL10725104 | 0.77 | AXL (0.40) | CSNK2A2CSNK2BDHODHKDM4E | |
| SCHEMBL5102002 | 0.76 | ALOX15 (0.66) | CSNK2A2CSNK2BDHODHKDM4EALOX15 | |
| SCHEMBL27716049 | 0.75 | ESR1 (0.57) | KDM4EALOX15ALDH1A1SMN1; SMN2MCL1 | |
| SCHEMBL24759619 | 0.73 | DHODH (0.42) | CSNK2A2CSNK2BDHODHKDM4EALOX15 | |
| SCHEMBL1016413 | 0.72 | MGAM (0.58) | KDM4EALOX15ALDH1A1SMN1; SMN2NAPRT | |
| SCHEMBL18320800 | 0.71 | KDM4E (0.47) | CSNK2A2CSNK2BDHODHKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207677-A1 | Napthyridine Compounds As Rock Inhibitors | GPC BIOTECH AG (DE) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207677-A1 | Napthyridine Compounds As Rock Inhibitors | ROCK2, ROCK1, RHOT2 | CSNK2A2 1534/4885CSNK2B 1805/4885DHODH 1456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.