Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 6/20 | 0.54 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.54 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.35 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25229791 | 0.94 | TEAD1 (0.49) | TEAD1TEAD3GNAI3GNAO1GNAI1 | |
| SCHEMBL20892891 | 0.90 | TEAD1 (0.45) | TEAD1TEAD3GNAI3GNAO1GNAI1 | |
| SCHEMBL16030874 | 0.85 | TEAD1 (0.56) | TEAD1TEAD3GNAI3GNAO1GNAI1 | |
| SCHEMBL17085551 | 0.85 | TEAD1 (0.49) | TEAD1TEAD3JAK2JAK1JAK3 | |
| SCHEMBL18333367 | 0.84 | TEAD1 (0.55) | TEAD1TEAD3JAK2JAK1JAK3 | |
| SCHEMBL18904847 | 0.82 | THRA (0.54) | TEAD1TEAD3JAK2JAK1JAK3 | |
| SCHEMBL17007588 | 0.81 | TEAD1 (0.56) | TEAD1TEAD3JAK2JAK1JAK3 | |
| SCHEMBL14393565 | 0.81 | GNAI3 (0.40) | TEAD1TEAD3GNAI3GNAO1GNAI1 | |
| SCHEMBL25365820 | 0.81 | GNAI3 (0.40) | TEAD1TEAD3GNAI3GNAO1GNAI1 | |
| SCHEMBL24541727 | 0.80 | JAK3 (0.45) | TEAD1TEAD3JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250101241-A1 | ACTIVE ENERGY RAY CURABLE COMPOSITION | KJ CHEMICALS CORPORATION (JP) | 2025-03-27 | — | — | US | disclosed |
| EP-4435021-A1 | ACTIVE ENERGY RAY-CURABLE COMPOSITION | KJ Chemicals Corporation (JP) | 2024-09-25 | — | — | EP | disclosed |
| CN-118251428-A | Active energy ray-curable composition | 科巨希化学股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| US-20230391937-A1 | POLYMERIZABLE COMPOSITION, PRODUCT OF POLYMERIZATION OF SAME, AND MOLDED ARTICLE OBTAINED USING THESE | KJ CHEMICALS CORPORATION (JP) | 2023-12-07 | — | — | US | disclosed |
| EP-4230664-A1 | POLYMERIZABLE COMPOSITION, PRODUCT OF POLYMERIZATION OF SAME, AND MOLDED ARTICLE OBTAINED USING THESE | KJ Chemicals Corporation (JP) | 2023-08-23 | — | — | EP | disclosed |
| CN-116391002-A | Polymerizable composition, polymer thereof, and molded article obtained using same | 科巨希化学股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2023090302-A1 | ACTIVE ENERGY RAY-CURABLE COMPOSITION | ＫＪケミカルズ株式会社 | 2023-05-25 | — | — | WO | disclosed |
| WO-2022080493-A1 | POLYMERIZABLE COMPOSITION, PRODUCT OF POLYMERIZATION OF SAME, AND MOLDED ARTICLE OBTAINED USING THESE | ＫＪケミカルズ株式会社 | 2022-04-21 | — | — | WO | disclosed |
| US-11186574-B2 | Inhibitors of EGFR and/or HER2 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-11-30 | — | — | US | disclosed |
| US-10844077-B2 | Thiazolyl-containing compounds for treating proliferative diseases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-20200199121-A1 | INHIBITORS OF EGFR AND/OR HER2 AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. | 2020-06-25 | — | — | US | disclosed |
| US-20200165267-A1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-05-28 | — | — | US | disclosed |
| US-20160369135-A1 | ADHESIVE COMPOSITION | DONGWOO FINE-CHEM CO., LTD. (KR) | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165267-A1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | BTK, BCL9L, MCL1 | TEAD1 3313/4885TEAD3 3631/4885GNAI3 1757/4885 |
| US-20230391937-A1 | POLYMERIZABLE COMPOSITION, PRODUCT OF POLYMERIZATION OF SAME, AND MOLDED ARTICLE OBTAINED USING THESE | MTR, AHCY, MAT1A | TEAD1 4793/4885TEAD3 4839/4885GNAI3 4217/4885 |
| US-10844077-B2 | Thiazolyl-containing compounds for treating proliferative diseases | BTK, BCL9L, MCL1 | TEAD1 3313/4885TEAD3 3631/4885GNAI3 1757/4885 |
| US-11186574-B2 | Inhibitors of EGFR and/or HER2 and methods of use | EGFR, ERBB2, ERBB3 | TEAD1 1017/4885TEAD3 1028/4885GNAI3 1761/4885 |
| US-20200199121-A1 | INHIBITORS OF EGFR AND/OR HER2 AND METHODS OF USE | EGFR, ERBB2, ERBB3 | TEAD1 1017/4885TEAD3 1028/4885GNAI3 1761/4885 |
| US-20250101241-A1 | ACTIVE ENERGY RAY CURABLE COMPOSITION | PARP1, CAP1, XRN2 | TEAD1 2946/4885TEAD3 4200/4885GNAI3 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.