Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.41 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18332161 | 0.92 | GPR119 (0.47) | MMP13EPHX2GPR119STSKMT2A | |
| SCHEMBL18331685 | 0.89 | NOD2 (0.44) | KMT2ANOD2NOD1ALOX5MEN1 | |
| SCHEMBL18332392 | 0.85 | NOD2 (0.44) | KMT2ANOD2NOD1ALOX5MEN1 | |
| SCHEMBL18332173 | 0.84 | NOD2 (0.43) | KMT2ANOD2NOD1ALOX5MEN1 | |
| SCHEMBL18331687 | 0.83 | NOD2 (0.45) | NOD2NOD1ALOX5 | |
| SCHEMBL10003940 | 0.82 | NOD2 (0.51) | MMP13GPR119KMT2ANOD2NOD1 | |
| SCHEMBL10003000 | 0.81 | NOD2 (0.49) | MMP13GPR119KMT2ANOD2NOD1 | |
| SCHEMBL18332395 | 0.81 | HTR6 (0.49) | GPR119KMT2ANOD2NOD1SCN9A | |
| SCHEMBL10003307 | 0.79 | NOD2 (0.55) | MMP13GPR119KMT2ANOD2NOD1 | |
| SCHEMBL18331705 | 0.77 | NOD1 (0.47) | KMT2ANOD2NOD1ALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016204261-A1 | AMINOPYRAZOLE DERIVATIVES | 中外製薬株式会社 | 2016-12-22 | — | — | WO | disclosed |