SCHEMBL18333498

SCHEMBL18333498

CC1(C)OB(c2ccc3c(c2)Oc2ccccc2N3)OC1(C)C

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 6/20 0.52
▸ LPL P06858 11/20 0.46
▸ LIPG Q9Y5X9 11/20 0.46
▸ HTR2B P41595 1/20 0.40
▸ PRMT5 O14744 1/20 0.37
▸ WDR77 Q9BQA1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13058013 0.92 LIPG (0.46) ALOX5LPLLIPGPRMT5WDR77
SCHEMBL28726419 0.83 LIPG (0.56) ALOX5LPLLIPGHTR2B
SCHEMBL30869831 0.82 LIPG (0.46) ALOX5LPLLIPG
SCHEMBL47074 0.82 LPL (0.53) LPLLIPG
SCHEMBL10171009 0.77 ALDH1A1 (0.41) LPLLIPGPRMT5WDR77
SCHEMBL17065892 0.77 LIPG (0.47) LPLLIPGPRMT5WDR77
SCHEMBL10074112 0.77 LPL (0.48) LPLLIPG
SCHEMBL10074115 0.77 LPL (0.48) LPLLIPG
SCHEMBL30951705 0.76 LIPG (0.41) ALOX5LPLLIPGPRMT5WDR77
SCHEMBL22217016 0.76 LIPG (0.46) LPLLIPGPRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10935862-B2 Electrochromic compound, electrochromic composition, and electrochromic display element RICOH COMPANY, LTD. (JP) 2021-03-02 — — US disclosed
EP-3660123-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC DISPLAY ELEMENT Ricoh Company, Ltd. (JP) 2020-06-03 — — EP disclosed
US-20200089070-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC DISPLAY ELEMENT YAMAMOTO SATOSHI (JP) 2020-03-19 — — US disclosed
EP-3310877-B1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC DISPLAY ELEMENT RICOH CO LTD (JP) 2020-02-26 — — EP disclosed
US-20180173070-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC DISPLAY ELEMENT RICOH COMPANY, LTD. (JP) 2018-06-21 — — US disclosed
US-20180173070-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC DISPLAY ELEMENT RICOH COMPANY, LTD. (JP) 2018-06-21 — — US disclosed
WO-2016203773-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC DISPLAY ELEMENT RICOH COMPANY, LTD. (JP) 2016-12-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180173070-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC DISPLAY ELEMENT RPS23, RPS18, RPL13 ALOX5 4800/4885LPL 3489/4885LIPG 3081/4885
US-10935862-B2 Electrochromic compound, electrochromic composition, and electrochromic display element RPS23, RPS18, RPL13 ALOX5 4800/4885LPL 3489/4885LIPG 3081/4885
US-20200089070-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC DISPLAY ELEMENT RPS23, RPS18, RPL13 ALOX5 4800/4885LPL 3489/4885LIPG 3081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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