Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 14/20 | 0.46 |
| ▸ | LPL | P06858 | 13/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31116974 | 0.80 | PGR (0.47) | LIPGLPLPDK2PDK4 | |
| SCHEMBL29674722 | 0.78 | LPL (0.49) | LIPGLPLPRMT5WDR77BACE1 | |
| SCHEMBL29450660 | 0.78 | LPL (0.49) | LIPGLPLPRMT5WDR77BACE1 | |
| SCHEMBL70348 | 0.78 | LPL (0.49) | LIPGLPLPRMT5WDR77BACE1 | |
| SCHEMBL17065892 | 0.77 | LIPG (0.47) | LIPGLPLPRMT5WDR77P4HB | |
| SCHEMBL24275677 | 0.76 | LPL (0.46) | LIPGLPLBACE1P4HBROCK1 | |
| SCHEMBL17072886 | 0.76 | GAA (0.48) | LIPGLPLPRMT5WDR77P4HB | |
| SCHEMBL18333498 | 0.76 | ALOX5 (0.52) | LIPGLPLPRMT5WDR77 | |
| SCHEMBL15982219 | 0.76 | LPL (0.46) | LIPGLPLBACE1P4HBROCK1 | |
| SCHEMBL69358 | 0.75 | LIPG (0.47) | LIPGLPLP4HBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200223857-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC RING COMPOUND AND APPLICATION THEREOF | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2020-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223857-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC RING COMPOUND AND APPLICATION THEREOF | NNT, NPPA, NQO1 | LIPG 4739/4885LPL 4850/4885PDK2 2300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.