Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566956 | 1.00 | CRBN (0.42) | CRBNMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL5501059 | 0.80 | CTRB1 (0.42) | HTTF2PRSS1CTRB1 | |
| SCHEMBL567091 | 0.73 | LMNA (0.49) | MAPTLMNAHTTCYP2C19 | |
| SCHEMBL567665 | 0.73 | LMNA (0.49) | MAPTLMNAHTTCYP2C19 | |
| SCHEMBL4699124 | 0.70 | CRBN (0.54) | CRBNMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL536617 | 0.70 | GLA (0.47) | L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL567327 | 0.70 | GLA (0.47) | L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL7767198 | 0.69 | CRBN (0.49) | CRBNMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL7259274 | 0.69 | LMNA (0.49) | NPC1RAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL10865471 | 0.69 | CRBN (0.44) | CRBNMAPTL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035341-A1 | PROCEDE DE POLYMERISATION PAR VOIE CATALYTIQUE DE 1,4-DIOXANES-2,5-DIONES ET LES POLYMERES CORRESPONDANTS | MINASOLVE (FR) | 2012-02-09 | — | — | US | disclosed |
| WO-2010100390-A1 | CATALYTIC POLYMERIZATION METHOD FOR 1,4-DIOXANE-2,5-DIONES, AND CORRESPONDING POLYMERS | MINASOLVE (FR) | 2010-09-10 | — | — | WO | disclosed |