Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 8/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8713679 | 0.98 | TDP1 (0.64) | TDP1POLBL3MBTL1MAPTHTT | |
| SCHEMBL18355598 | 0.84 | TDP1 (0.49) | TDP1POLBL3MBTL1MAPTHTT | |
| SCHEMBL4140757 | 0.83 | TDP1 (0.45) | TDP1POLBMAPTHTTHSD17B10 | |
| SCHEMBL901472 | 0.82 | TDP1 (0.72) | TDP1POLBL3MBTL1MAPTHTT | |
| SCHEMBL854763 | 0.81 | HTT (0.44) | TDP1POLBL3MBTL1MAPTHTT | |
| SCHEMBL8610246 | 0.80 | TDP1 (0.69) | TDP1POLBL3MBTL1MAPTHTT | |
| Sumiki'S Acid SCHEMBL50822 | 0.80 | TDP1 (1.00) | TDP1POLBL3MBTL1MAPTHTT | |
| Sumiki'S Acid SCHEMBL29706392 | 0.80 | TDP1 (1.00) | TDP1POLBL3MBTL1MAPTHTT | |
| Ethylenediamine SCHEMBL29057803 | 0.79 | TDP1 (0.56) | TDP1POLBL3MBTL1MAPTHTT | |
| SCHEMBL4442918 | 0.78 | TDP1 (0.67) | TDP1POLBL3MBTL1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021062048-A2 | METHODS AND SYSTEMS FOR MODULATING HEPATIC GABA PRODUCTION OR RELEASE TO ALTER FOOD INTAKE IN MONOGASTRIC SPECIES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-04-01 | — | — | WO | claimed |
| US-20170081470-A1 | METHODS OF PRODUCING COMPOUNDS FROM 5-(HALOMETHYL)FURFURAL | MICROMIDAS, INC. (US) | 2017-03-23 | — | — | US | claimed |
| EP-3142997-A1 | METHODS OF PRODUCING COMPOUNDS FROM 5-(HALOMETHYL)FURFURAL | Micromidas, Inc. (US) | 2017-03-22 | — | — | EP | claimed |
| WO-2015175528-A1 | METHODS OF PRODUCING COMPOUNDS FROM 5-(HALOMETHYL)FURFURAL | MICROMIDAS, INC. (US) | 2015-11-19 | — | — | WO | claimed |
| US-8158206-B2 | Method for modifying wood and wood thereby obtained | TRANSFURANS CHEMICALS (BE) | 2012-04-17 | — | — | US | claimed |
| EP-2035198-B1 | METHOD FOR MODIFYING WOOD AND WOOD THEREBY OBTAINED | TRANSFURANS CHEMICALS (BE) | 2012-01-04 | — | — | EP | claimed |
| EP-2384338-A2 | GLP-1 ANALOGS AND USES THEREOF | Panacea Biotec Limited (IN) | 2011-11-09 | — | — | EP | claimed |
| US-20110269680-A1 | GLP-1 ANALOGS AND USES THEREOF | PANACEA BIOTEC LIMITED (IN) | 2011-11-03 | — | — | US | claimed |
| WO-2011096812-A1 | METHOD AND APPARATUS FOR MODIFYING WOOD, AND WOOD PRODUCT | VIA INGENIO B.V. (NL) | 2011-08-11 | — | — | WO | claimed |
| WO-2010076809-A2 | GLP-1 ANALOGS AND USES THEREOF | PANACEA BIOTEC LTD (IN) | 2010-07-08 | — | — | WO | claimed |
| US-20100062276-A1 | METHOD FOR MODIFYING WOOD AND WOOD THEREBY OBTAINED | TRANSFURANS CHEMICALS (BE) | 2010-03-11 | — | — | US | claimed |
| EP-2096111-A1 | PYRAZOLES AND USE THEREOF AS DRUGS | Japan Tobacco Inc. (JP) | 2009-09-02 | — | — | EP | claimed |
| EP-2035198-A1 | METHOD FOR MODIFYING WOOD AND WOOD THEREBY OBTAINED | Transfurans Chemicals (BE) | 2009-03-18 | — | — | EP | claimed |
| US-20090036450-A1 | PYRAZOLE COMPOUNDS AND USE THEREOF | JAPAN TOBACCO, INC. (JP) | 2009-02-05 | — | — | US | claimed |
| WO-2007147804-A1 | METHOD FOR MODIFYING WOOD AND WOOD THEREBY OBTAINED | TRANSFURANS CHEMICALS (BE) | 2007-12-27 | — | — | WO | claimed |
| CN-117305203-A | Recombinant bacterium for catalytic synthesis of 5-aminomethyl-2-furoic acid and application thereof | 华南理工大学 | 2023-12-29 | — | — | CN | disclosed |
| US-20230390308-A1 | URSODEOXYCHOLIC ACID DERIVATIVES FOR THE TREATMENT OF POLYCYSTIC DISEASES | UNIV DEL PAIS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) | 2023-12-07 | — | — | US | disclosed |
| US-20050222088-A1 | Synthesis of chiral furan amino acids as novel peptide building blocks | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-10-06 | — | — | US | disclosed |
| CN-1478078-A | Nitrogen-containing aromatic ring derivatives | ������������ʽ���� | 2004-02-25 | — | — | CN | disclosed |
| CN-1437587-A | Benzoxazepinones and their use as squalene synthetase inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-08-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222088-A1 | Synthesis of chiral furan amino acids as novel peptide building blocks | DNPEP, ANPEP, PTMS | TDP1 4328/4885POLB 2481/4885L3MBTL1 1280/4885 |
| US-20230390308-A1 | URSODEOXYCHOLIC ACID DERIVATIVES FOR THE TREATMENT OF POLYCYSTIC DISEASES | PKD1, PKD2, SLC10A1 | TDP1 4571/4885POLB 1295/4885L3MBTL1 4134/4885 |
| US-20110269680-A1 | GLP-1 ANALOGS AND USES THEREOF | GLP1R, GIPR, IAPP | TDP1 2534/4885POLB 4840/4885L3MBTL1 1198/4885 |
| US-20090036450-A1 | PYRAZOLE COMPOUNDS AND USE THEREOF | PYGL, GYS2, G6PC1 | TDP1 993/4885POLB 2667/4885L3MBTL1 3944/4885 |
| US-20170081470-A1 | METHODS OF PRODUCING COMPOUNDS FROM 5-(HALOMETHYL)FURFURAL | HDHD5, HPD, DCXR | TDP1 3104/4885POLB 3100/4885L3MBTL1 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.