SCHEMBL18362467

SCHEMBL18362467

C=CC(=O)NCCNCCC(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 2/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
GAA P10253 2/20 0.36
EPHX2 P34913 1/20 0.34
MLYCD O95822 1/20 0.33
CTSK P43235 2/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
TGM2 P21980 3/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HTT P42858 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18354072 0.84 ZDHHC20 (0.50) ZDHHC20ZDHHC2TDP1ALDH1A1TSHR
SCHEMBL3485766 0.81 EPHX2 (0.40) TDP1TSHRGAAEPHX2MLYCD
SCHEMBL3664095 0.80 TDP1 (0.50) TDP1ALDH1A1GAACTSKMAOA
SCHEMBL29004029 0.79 ZDHHC20 (0.38) ZDHHC20ZDHHC2TDP1ALDH1A1TSHR
SCHEMBL16664772 0.78 HDAC6 (0.37) TDP1GAAEPHX2MLYCDCTSK
SCHEMBL12318662 0.78 TDP1 (0.51) ZDHHC20ZDHHC2TDP1ALDH1A1TSHR
SCHEMBL9138923 0.78 TSHR (0.46) ZDHHC20ZDHHC2TDP1ALDH1A1TSHR
SCHEMBL23675898 0.78 ZDHHC20 (0.44) ZDHHC20ZDHHC2TDP1ALDH1A1TSHR
SCHEMBL3901763 0.77 ALDH1A1 (0.59) ZDHHC20ZDHHC2TDP1ALDH1A1TSHR
SCHEMBL23521793 0.77 ALDH1A1 (0.38) ALDH1A1TSHRGAAEPHX2MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230124554-A1 FREE-STANDING NON-FOULING POLYMERS, THEIR COMPOSITIONS, AND RELATED MONOMERS UNIVERSITY OF WASHINGTON (US) 2023-04-20 US disclosed
US-20190002625-A1 FREE-STANDING NON-FOULING POLYMERS, THEIR COMPOSITIONS, AND RELATED MONOMERS UNIVERSITY OF WASHINGTON (US) 2019-01-03 US disclosed
WO-2017003639-A2 FREE-STANDING NON-FOULING POLYMERS, THEIR COMPOSITIONS, AND RELATED MONOMERS UNIVERSITY OF WASHINGTON (US) 2017-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190002625-A1 FREE-STANDING NON-FOULING POLYMERS, THEIR COMPOSITIONS, AND RELATED MONOMERS FGB, MSN, FN1 ZDHHC20 3149/4885ZDHHC2 3773/4885TDP1 1744/4885
US-20230124554-A1 FREE-STANDING NON-FOULING POLYMERS, THEIR COMPOSITIONS, AND RELATED MONOMERS FGB, FN1, MSN ZDHHC20 3148/4885ZDHHC2 3622/4885TDP1 1926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.