Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18355083 | 1.00 | OGA (0.34) | OGAMAPK1L3MBTL1THRB | |
| SCHEMBL18355210 | 0.83 | ACHE (0.31) | — | |
| SCHEMBL22417213 | 0.83 | ALKBH2 (0.35) | — | |
| SCHEMBL16835093 | 0.83 | ALKBH2 (0.35) | — | |
| SCHEMBL18355180 | 0.82 | — | — | |
| SCHEMBL16835035 | 0.82 | — | — | |
| SCHEMBL22394435 | 0.81 | OGA (0.41) | OGA | |
| SCHEMBL20193899 | 0.81 | OGA (0.41) | OGA | |
| SCHEMBL18360564 | 0.77 | OGA (0.34) | OGAMAPK1L3MBTL1 | |
| SCHEMBL16835233 | 0.74 | P2RX7 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083601-B1 | PIPERIDINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS SA (ES) | 2020-09-09 | — | — | EP | disclosed |
| US-9981942-B2 | Piperidine derivatives having multimodal activity against pain | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 2018-05-29 | — | — | US | disclosed |
| US-9981942-B2 | Piperidine derivatives having multimodal activity against pain | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 2018-05-29 | — | — | US | disclosed |
| US-20170001978-A1 | PIPERIDINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001978-A1 | PIPERIDINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | OPRD1, OPRM1, OPRK1 | OGA 2594/4885MAPK1 3441/4885L3MBTL1 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.