Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357761 | 0.82 | FFAR4 (0.46) | FFAR4KCNH2SLC6A4LIPEKCNA5 | |
| SCHEMBL18357421 | 0.82 | KCNH2 (0.42) | KCNH2CHRM4SLC6A4LIPEKCNA5 | |
| SCHEMBL18357665 | 0.79 | FFAR4 (0.43) | FFAR4KCNH2CHRM4LIPEKCNA5 | |
| SCHEMBL24199057 | 0.78 | CHRM4 (0.43) | FFAR4KCNH2CHRM4SLC6A4KCNA5 | |
| SCHEMBL18357721 | 0.75 | CHRM4 (0.41) | FFAR4KCNH2CHRM4SLC6A4DRD3 | |
| SCHEMBL20345536 | 0.75 | CHRM4 (0.41) | FFAR4KCNH2CHRM4SLC6A4DRD3 | |
| SCHEMBL18357675 | 0.75 | LIPE (0.42) | FFAR4KCNH2CHRM4LIPEKCNA5 | |
| SCHEMBL22904442 | 0.73 | LCAT (0.47) | FFAR4KCNH2CHRM4LIPEKCNA5 | |
| SCHEMBL17878026 | 0.73 | ALDH1A1 (0.48) | KCNH2CHRM4SLC6A4DRD3KCNA5 | |
| SCHEMBL20345588 | 0.72 | LOXL2 (0.35) | FFAR4CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230014173-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2023-01-19 | — | — | US | disclosed |
| US-11180472-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2021-11-23 | — | — | US | disclosed |
| US-20200239434-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2020-07-30 | — | — | US | disclosed |
| US-20190330189-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2019-10-31 | — | — | US | disclosed |
| US-10364232-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2019-07-30 | — | — | US | disclosed |
| US-20180186768-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-05 | — | — | US | disclosed |
| US-20180186768-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-05 | — | — | US | disclosed |
| WO-2017001660-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180472-B2 | Antibacterial compounds | FDPS, SQOR, NDUFS3 | FFAR4 4595/4885KCNH2 3752/4885CHRM4 3837/4885 |
| US-20190330189-A1 | ANTIBACTERIAL COMPOUNDS | FDPS, SQOR, NDUFS3 | FFAR4 4595/4885KCNH2 3752/4885CHRM4 3837/4885 |
| US-10364232-B2 | Antibacterial compounds | FDPS, SQOR, NDUFS3 | FFAR4 4595/4885KCNH2 3752/4885CHRM4 3837/4885 |
| US-20180186768-A1 | Antibacterial Compounds | FDPS, SQOR, NDUFS3 | FFAR4 4595/4885KCNH2 3752/4885CHRM4 3837/4885 |
| US-20230014173-A1 | Antibacterial Compounds | FDPS, SQOR, NDUFS3 | FFAR4 4595/4885KCNH2 3752/4885CHRM4 3837/4885 |
| US-20200239434-A1 | ANTIBACTERIAL COMPOUNDS | FDPS, SQOR, NDUFS3 | FFAR4 4595/4885KCNH2 3752/4885CHRM4 3837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.