Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.51 |
| ▸ | GAA | P10253 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 4/20 | 0.49 |
| ▸ | GSK3B | P49841 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037541 | 0.83 | MAPT (0.55) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL3040357 | 0.81 | KMT2A (0.60) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL6002938 | 0.79 | MAPT (0.43) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL9097624 | 0.78 | GAA (0.50) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL3030170 | 0.77 | MAPT (0.55) | MAPTGAAALDH1A1KMT2ATDP1 | |
| N-Benzoylaminorhodanine SCHEMBL8595198 | 0.74 | MAPT (0.74) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL6783895 | 0.74 | MAPT (0.50) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL4394297 | 0.71 | CYP1A2 (0.57) | MAPTGAAALDH1A1TDP1CASP6 | |
| SCHEMBL181796 | 0.69 | KMT2A (0.69) | MAPTGAAALDH1A1KMT2ARECQL | |
| SCHEMBL9667997 | 0.69 | CYP1A2 (0.46) | MAPTGAAALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450159-A | ORGAN TRANSPLANTS; IMMUNOLOGY | THE UPJOHN COMPANY (US) | 1984-05-22 | — | — | US | claimed |
| JP-62067057-A | — | — | None | — | — | JP | disclosed |
| US-8338465-B2 | Cyclic carboxylic acid rhodanine derivatives for the treatment and prevention of tuberculosis | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338465-B2 | Cyclic carboxylic acid rhodanine derivatives for the treatment and prevention of tuberculosis | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| EP-1923227-B1 | A structure with a built-in recording medium, a laminate comprising the structure and method for recording in non-contact manner using the structure and the laminate | LINTEC CORP (JP) | 2011-05-11 | — | — | EP | disclosed |
| US-7939464-B2 | Resin laminate material with a built-in recording medium with a means for rewriting visible information with a laser light in a non-contact manner; recording and erasing of information can be conducted by irradiation with a laser light from outside | LINTEC CORPORATION (JP) | 2011-05-10 | — | — | US | disclosed |
| US-20100210577-A1 | CYCLIC CARBOXYLIC ACID RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF TUBERCULOSIS | CORNELL RESEARCH FOUNDATION, INC. | 2010-08-19 | — | — | US | disclosed |
| US-20100210577-A1 | CYCLIC CARBOXYLIC ACID RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF TUBERCULOSIS | CORNELL RESEARCH FOUNDATION, INC. | 2010-08-19 | — | — | US | disclosed |
| US-20080193397-A1 | Use of Peroxide Decomposers Method For the Treatment of a Material Other Than the Human Body | BASF AKTIENGESELLSCAFT (DE) | 2008-08-14 | — | — | US | disclosed |
| US-5041667-A | Process for producing chlorophenylhydrazine compounds | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0208477-B1 | PROCESS FOR PRODUCING CHLOROPHENYLHYDRAZINE COMPOUNDS | KONICA CORPORATION (JP) | 1989-03-15 | — | — | EP | disclosed |
| JP-S6267057-A | PRODUCTION OF CHLOROPHENYLHYDRAZINE COMPOUND | KONISHIROKU PHOTO IND CO LTD | 1987-03-26 | — | — | JP | disclosed |
| EP-0208477-A1 | Process for producing chlorophenylhydrazine compounds | KONICA CORPORATION (JP) | 1987-01-14 | — | — | EP | disclosed |
| US-4403051-A | NONVISCOUS MIXTURE OF POLYVINYL ALCOHOL AND PULP | KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) | 1983-09-06 | — | — | US | disclosed |
| US-4180405-A | COLOR-FORMING LACTONES OR SPIROPYRANS WITH CYCLIC POLYKETO COLOR PRECURSOR | GRAPHIC CONTROLS CORPORATION (US) | 1979-12-25 | — | — | US | disclosed |
| US-4097288-A | Heat sensitive recording composition containing a complexed phenolics and a spiropyran or leuco lactone | GRAPHIC CONTROLS CORPORATION | 1978-06-27 | — | — | US | disclosed |
| US-4074050-A | COLOR FORMER | HODOGAYA CHEMICAL CO., LTD. (JA) | 1978-02-14 | — | — | US | disclosed |
| US-4073614-A | Mixture of benzoxazines and benzodioxanes which may be used as color formers | HODOGAYA CHEMICAL CO., LTD. (JA) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080193397-A1 | Use of Peroxide Decomposers Method For the Treatment of a Material Other Than the Human Body | GPX4, LPO, GPX1 | MAPT 2926/4885GAA 1162/4885ALDH1A1 569/4885 |
| US-20100210577-A1 | CYCLIC CARBOXYLIC ACID RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF TUBERCULOSIS | RARG, SDHA, RARS2 | MAPT 3973/4885GAA 162/4885ALDH1A1 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.