Sugi Predict

Sugi Predict / Compounds / SCHEMBL18372159

SCHEMBL18372159

SCHEMBL18372159

O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2ccc3c4ccc(-c5ccc(P(=O)(c6ccccc6)c6ccccc6)cc5)cc4c4ccccc4c3c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.39
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ PRMT5 O14744 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ CA4 P22748 1/20 0.37
▸ CA5A P35218 1/20 0.37
▸ PLA2G2A P14555 1/20 0.36
▸ PLA2G4A P47712 1/20 0.36
▸ NR4A2 P43354 1/20 0.36
▸ ESR1 P03372 1/20 0.35
▸ TNKS2 Q9H2K2 1/20 0.35
▸ TOP1 P11387 1/20 0.35
▸ NOTUM Q6P988 1/20 0.34
▸ LCK P06239 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18372113 1.00 LMNA (0.43) LMNANPSR1MEN1KMT2APRMT5
SCHEMBL18253836 1.00 LMNA (0.43) LMNANPSR1MEN1KMT2APRMT5
SCHEMBL18253835 1.00 LMNA (0.43) LMNANPSR1MEN1KMT2APRMT5
SCHEMBL18372154 0.96 PRMT5 (0.41) LMNANPSR1MEN1KMT2APRMT5
SCHEMBL20746675 0.94 MEN1 (0.40) LMNANPSR1MEN1KMT2APRMT5
SCHEMBL21842613 0.89 HDAC8 (0.39) LMNAMEN1KMT2APRMT5PLA2G2A
SCHEMBL18372016 0.88 RAB9A (0.40) LMNANPSR1MEN1KMT2APRMT5
SCHEMBL9927207 0.88 LMNA (0.46) LMNANPSR1MEN1KMT2AKDM4E
SCHEMBL18372013 0.88 LMNA (0.46) LMNANPSR1MEN1KMT2AKDM4E
SCHEMBL18253848 0.86 MAPT (0.36) LMNAMEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10211404-B2 Compound, material for organic electroluminescent elements, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-02-19 — — US disclosed
US-20170012209-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-01-12 — — US disclosed
US-20170012209-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-01-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170012209-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE PIEZO1, TERT, TPR LMNA 2224/4885NPSR1 4592/4885MEN1 1382/4885
US-10211404-B2 Compound, material for organic electroluminescent elements, organic electroluminescent element and electronic device PIEZO1, TERT, TPR LMNA 2224/4885NPSR1 4592/4885MEN1 1382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.