Sugi Predict

Sugi Predict / Compounds / SCHEMBL18372154

SCHEMBL18372154

SCHEMBL18372154

O=P(c1ccc(-c2ccccc2)cc1)(c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccc3c4ccc(-c5ccc(P(=O)(c6ccc(-c7ccccc7)cc6)c6ccc(-c7ccccc7)cc6)cc5)cc4c4ccccc4c3c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT5 O14744 1/20 0.41
▸ PLA2G2A P14555 1/20 0.39
▸ PLA2G4A P47712 1/20 0.39
▸ LMNA P02545 2/20 0.39
▸ NR4A2 P43354 1/20 0.39
▸ TNKS2 Q9H2K2 1/20 0.39
▸ NOTUM Q6P988 1/20 0.38
▸ ALOX5 P09917 1/20 0.38
▸ ACP3 P15309 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ APAF1 O14727 1/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ THRB P10828 1/20 0.37
▸ XBP1 P17861 1/20 0.37
▸ PTBP1 P26599 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ GALK1 P51570 1/20 0.37
▸ BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18253835 0.96 LMNA (0.43) PRMT5PLA2G2APLA2G4ALMNANR4A2
SCHEMBL18253836 0.96 LMNA (0.43) PRMT5PLA2G2APLA2G4ALMNANR4A2
SCHEMBL18372159 0.96 LMNA (0.43) PRMT5PLA2G2APLA2G4ALMNANR4A2
SCHEMBL18372113 0.96 LMNA (0.43) PRMT5PLA2G2APLA2G4ALMNANR4A2
SCHEMBL20746675 0.94 MEN1 (0.40) PRMT5PLA2G2APLA2G4ALMNANR4A2
SCHEMBL18372016 0.92 RAB9A (0.40) PRMT5LMNATNKS2NOTUMALOX5
SCHEMBL21842613 0.89 HDAC8 (0.39) PRMT5PLA2G2APLA2G4ALMNANR4A2
SCHEMBL15479331 0.85 LMNA (0.39) PRMT5PLA2G2APLA2G4ALMNATNKS2
SCHEMBL1614546 0.85 ALDH1A1 (0.50) PLA2G2APLA2G4ALMNATNKS2ALOX5
SCHEMBL14479463 0.85 ALDH1A1 (0.50) PLA2G2APLA2G4ALMNATNKS2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10211404-B2 Compound, material for organic electroluminescent elements, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-02-19 — — US disclosed
US-20170012209-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-01-12 — — US disclosed
US-20170012209-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-01-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170012209-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE PIEZO1, TERT, TPR PRMT5 2679/4885PLA2G2A 4416/4885PLA2G4A 4608/4885
US-10211404-B2 Compound, material for organic electroluminescent elements, organic electroluminescent element and electronic device PIEZO1, TERT, TPR PRMT5 2679/4885PLA2G2A 4416/4885PLA2G4A 4608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.