Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20415563 | 0.87 | CMA1 (0.51) | — | |
| SCHEMBL18374166 | 0.85 | ALDH1A1 (0.49) | — | |
| SCHEMBL18374388 | 0.84 | ACE (0.49) | OPRM1OPRD1 | |
| SCHEMBL18374556 | 0.84 | CMA1 (0.44) | OPRM1OPRD1 | |
| SCHEMBL29565052 | 0.83 | OPRM1 (0.54) | OPRM1OPRD1SLC6A2 | |
| SCHEMBL28918688 | 0.83 | ACE (0.54) | OPRM1OPRD1 | |
| SCHEMBL28918687 | 0.83 | ACE (0.54) | OPRM1OPRD1 | |
| SCHEMBL21581709 | 0.82 | OPRM1 (0.58) | OPRM1OPRD1 | |
| SCHEMBL26454172 | 0.82 | OPRM1 (0.58) | OPRM1OPRD1 | |
| SCHEMBL29496921 | 0.81 | SLC6A2 (0.66) | OPRM1OPRD1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365215-B2 | Method for preventing, improving, or treating inflammatory bowel disease | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2022-06-21 | — | — | US | disclosed |
| US-20180208625-A1 | METHOD FOR PREVENTING, IMPROVING, OR TREATING INFLAMMATORY BOWEL DISEASE | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-07-26 | — | — | US | disclosed |
| US-20170008924-A1 | PYRROLIDINE CARBOXAMIDO DERIVATIVES AND METHODS FOR PREPARING AND USING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2017-01-12 | — | — | US | disclosed |
| WO-2017008033-A1 | PYRROLIDINE CARBOXAMIDO DERIVATIVES AND METHODS FOR PREPARING AND USING THE SAME | Reasearch & Business Foundation Sungkyunkwan University (KR) | 2017-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208625-A1 | METHOD FOR PREVENTING, IMPROVING, OR TREATING INFLAMMATORY BOWEL DISEASE | SI, NOD2, TNF | OPRM1 3659/4885OPRD1 2585/4885SLC6A2 4635/4885 |
| US-20170008924-A1 | PYRROLIDINE CARBOXAMIDO DERIVATIVES AND METHODS FOR PREPARING AND USING THE SAME | NOD2, SI, APC | OPRM1 2788/4885OPRD1 1595/4885SLC6A2 4862/4885 |
| US-11365215-B2 | Method for preventing, improving, or treating inflammatory bowel disease | SI, NOD2, TNF | OPRM1 3659/4885OPRD1 2585/4885SLC6A2 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.