Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MGLL | Q99685 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18375290 | 0.88 | ALDH1A1 (0.53) | ALDH1A1KMT2AMGLLSMN1; SMN2GAA | |
| SCHEMBL28211429 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMGLLSMN1; SMN2 | |
| SCHEMBL15663909 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAMGLL | |
| SCHEMBL15664050 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAMGLL | |
| SCHEMBL29586254 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAMGLL | |
| SCHEMBL29586658 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNAMGLL | |
| SCHEMBL9046891 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL8134776 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL8701763 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7423587 | 0.84 | MGLL (0.53) | ALDH1A1MEN1KMT2ALMNAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774722-B1 | OPIOID RECEPTOR MODULATORS AND PRODUCTS AND METHODS RELATED THERETO | EPIODYNE INC (US) | 2024-07-24 | — | — | EP | disclosed |
| US-11484525-B2 | Mu opioid receptor modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-11-01 | — | — | US | disclosed |
| US-11352316-B2 | Opioid receptor modulators and products and methods related thereto | EPIODYNE, INC. (US) | 2022-06-07 | — | — | US | disclosed |
| EP-3319444-B1 | MU OPIOID RECEPTOR MODULATORS | UNIV CALIFORNIA (US) | 2022-03-09 | — | — | EP | disclosed |
| US-20210052548-A1 | MU OPIOID RECEPTOR MODULATORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-02-25 | — | — | US | disclosed |
| US-10702498-B2 | MU opioid receptor modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-07 | — | — | US | disclosed |
| US-20200109126-A1 | MU OPIOID RECEPTOR MODULATORS | UNIV CALIFORNIA (US) | 2020-04-09 | — | — | US | disclosed |
| US-20190076398-A1 | MU OPIOID RECEPTOR MODULATORS | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2019-03-14 | — | — | US | disclosed |
| WO-2017007695-A1 | MU OPIOID RECEPTOR MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11484525-B2 | Mu opioid receptor modulators | OPRM1, OPRK1, OPRD1 | ALDH1A1 1790/4885MEN1 4881/4885KMT2A 3011/4885 |
| US-10702498-B2 | MU opioid receptor modulators | OPRM1, OPRK1, OPRD1 | ALDH1A1 1790/4885MEN1 4881/4885KMT2A 3011/4885 |
| US-11352316-B2 | Opioid receptor modulators and products and methods related thereto | OPRM1, OPRD1, OPRK1 | ALDH1A1 1571/4885MEN1 4643/4885KMT2A 2424/4885 |
| US-20190076398-A1 | MU OPIOID RECEPTOR MODULATORS | OPRM1, OPRK1, OPRD1 | ALDH1A1 1790/4885MEN1 4881/4885KMT2A 3011/4885 |
| US-20210052548-A1 | MU OPIOID RECEPTOR MODULATORS | OPRM1, OPRK1, OPRD1 | ALDH1A1 1790/4885MEN1 4881/4885KMT2A 3011/4885 |
| US-20200109126-A1 | MU OPIOID RECEPTOR MODULATORS | OPRM1, OPRK1, OPRD1 | ALDH1A1 1790/4885MEN1 4881/4885KMT2A 3011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.