Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18375511 | 0.88 | ALDH1A1 (0.67) | ALDH1A1MGLLGAAKMT2ASMN1; SMN2 | |
| SCHEMBL7257343 | 0.82 | MGLL (0.57) | ALDH1A1MGLLGAAKMT2ABCL9 | |
| SCHEMBL6984561 | 0.82 | ALDH1A1 (0.54) | ALDH1A1GAAKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6082739 | 0.80 | KMT2A (0.47) | ALDH1A1MGLLKMT2ANPC1RAB9A | |
| SCHEMBL15663909 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MGLLGAAKMT2ASMN1; SMN2 | |
| SCHEMBL29586254 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MGLLGAAKMT2ANPC1 | |
| SCHEMBL29586658 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MGLLGAAKMT2ANPC1 | |
| SCHEMBL15664050 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MGLLGAAKMT2ABCL9 | |
| SCHEMBL29587030 | 0.79 | GAA (0.49) | ALDH1A1MGLLGAAKMT2ASMN1; SMN2 | |
| SCHEMBL13120799 | 0.79 | MAPT (0.52) | ALDH1A1MGLLACHEKMT2ABCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11484525-B2 | Mu opioid receptor modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-11-01 | — | — | US | disclosed |
| EP-3319444-B1 | MU OPIOID RECEPTOR MODULATORS | UNIV CALIFORNIA (US) | 2022-03-09 | — | — | EP | disclosed |
| US-20210052548-A1 | MU OPIOID RECEPTOR MODULATORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-02-25 | — | — | US | disclosed |
| US-10702498-B2 | MU opioid receptor modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-07 | — | — | US | disclosed |
| US-20200109126-A1 | MU OPIOID RECEPTOR MODULATORS | UNIV CALIFORNIA (US) | 2020-04-09 | — | — | US | disclosed |
| US-20190076398-A1 | MU OPIOID RECEPTOR MODULATORS | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2019-03-14 | — | — | US | disclosed |
| WO-2017007695-A1 | MU OPIOID RECEPTOR MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11484525-B2 | Mu opioid receptor modulators | OPRM1, OPRK1, OPRD1 | ALDH1A1 1790/4885MGLL 989/4885ACHE 552/4885 |
| US-10702498-B2 | MU opioid receptor modulators | OPRM1, OPRK1, OPRD1 | ALDH1A1 1790/4885MGLL 989/4885ACHE 552/4885 |
| US-20190076398-A1 | MU OPIOID RECEPTOR MODULATORS | OPRM1, OPRK1, OPRD1 | ALDH1A1 1790/4885MGLL 989/4885ACHE 552/4885 |
| US-20210052548-A1 | MU OPIOID RECEPTOR MODULATORS | OPRM1, OPRK1, OPRD1 | ALDH1A1 1790/4885MGLL 989/4885ACHE 552/4885 |
| US-20200109126-A1 | MU OPIOID RECEPTOR MODULATORS | OPRM1, OPRK1, OPRD1 | ALDH1A1 1790/4885MGLL 989/4885ACHE 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.