Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | ACR | P10323 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMO | Q99835 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855964 | 0.88 | SMN1; SMN2 (0.80) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL8319324 | 0.83 | RAB9A (0.64) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL28665987 | 0.81 | SMN1; SMN2 (0.76) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL5232976 | 0.81 | SMN1; SMN2 (1.00) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL2011651 | 0.81 | RAB9A (0.77) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL4122902 | 0.80 | TRPV1 (0.65) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL14855798 | 0.80 | SMN1; SMN2 (0.75) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7209259 | 0.79 | LMNA (0.67) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL30539412 | 0.79 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL9645988 | 0.79 | RAB9A (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170007589-A1 | Compositions For Treating Retinal Degeneration And Methods of Production and Use Thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170007589-A1 | Compositions For Treating Retinal Degeneration And Methods of Production and Use Thereof | ALDH1A2, PDE6D, PDE6H | ALDH1A1 465/4885MEN1 4711/4885KMT2A 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.