Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18392402 | 0.87 | CCR6 (0.47) | CAMK2DCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL18392166 | 0.86 | S100A4 (0.54) | MGAMGAASIMGAM2CAMK2D | |
| SCHEMBL18392216 | 0.85 | PTGS2 (0.48) | GAACAMK2DS100A4CCNB2CDK1 | |
| SCHEMBL18392173 | 0.84 | ABCG2 (0.54) | CCNB2CDK1CCNB1CCNB3LMNA | |
| SCHEMBL20365540 | 0.83 | PRKCB (0.39) | GABRA1GABRB1GABRA3GABRB2KMT2A | |
| SCHEMBL18392217 | 0.78 | GSK3B (0.47) | CAMK2DCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL18392175 | 0.77 | CCR6 (0.58) | GAALMNAHPGDKMT2AHSD17B10 | |
| SCHEMBL30277945 | 0.76 | LMNA (0.53) | MGAMGAASIMGAM2CAMK2D | |
| SCHEMBL18392203 | 0.75 | MEN1 (0.54) | MGAMGAASIMGAM2CAMK2D | |
| SCHEMBL29094072 | 0.75 | PTGS2 (0.49) | MGAMGAASIMGAM2CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319940-B1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | UNIV BRAUNSCHWEIG TECH (DE) | 2019-05-29 | — | — | EP | disclosed |
| EP-3319940-B1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | UNIV BRAUNSCHWEIG TECH (DE) | 2019-05-29 | — | — | EP | disclosed |
| US-10287271-B2 | Indole compounds having antiprotozoal activity and its use as well as methods for producing the same | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2019-05-14 | — | — | US | disclosed |
| US-10287271-B2 | Indole compounds having antiprotozoal activity and its use as well as methods for producing the same | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2019-05-14 | — | — | US | disclosed |
| US-20180194750-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2018-07-12 | — | — | US | disclosed |
| US-20180194750-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2018-07-12 | — | — | US | disclosed |
| US-20180194750-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2018-07-12 | — | — | US | disclosed |
| WO-2017008826-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2017-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194750-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | IDO1, IDO2, INMT | MGAM 1572/4885GAA 2354/4885SI 351/4885 |
| US-10287271-B2 | Indole compounds having antiprotozoal activity and its use as well as methods for producing the same | IDO1, IDO2, INMT | MGAM 1618/4885GAA 2635/4885SI 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.