Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17555032 | 0.99 | DNM1 (0.48) | KMT2AMEN1SMN1; SMN2TP53MAPK1 | |
| Bromide SCHEMBL29825165 | 0.97 | DNM1 (0.49) | KMT2AMEN1SMN1; SMN2TP53MAPK1 | |
| Sulfuric Acid SCHEMBL6476044 | 0.92 | PLAAT5 (0.43) | KMT2AMEN1SMN1; SMN2TP53MAPK1 | |
| Hydrochloric Acid SCHEMBL4884176 | 0.92 | BCHE (0.53) | KMT2AMEN1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL18314761 | 0.92 | BCHE (0.40) | KMT2AMEN1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL31476923 | 0.90 | BCHE (0.51) | KMT2AMEN1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL18314766 | 0.87 | PSMD14 (0.40) | KMT2AMEN1SMN1; SMN2TP53MAPK1 | |
| Cetalkonium SCHEMBL27745607 | 0.85 | DNM1 (0.56) | KMT2AMEN1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL17472220 | 0.84 | DNM1 (0.53) | KMT2AMEN1SMN1; SMN2TP53MAPK1 | |
| Sulfuric Acid SCHEMBL6472910 | 0.84 | BCHE (0.46) | SMN1; SMN2DNM1BCHEACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113638230-A | Novel sizing agent and preparation method thereof | 四川聚塔科技股份有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-111471130-A | Resistance reducing agent for online mixing variable viscosity fracturing and preparation method thereof | 北京金圣奥能源技术有限公司 | 2020-07-31 | — | — | CN | claimed |
| US-20190217311-A1 | CATIONIC POLYMER SELECTIVE DEPRESSANTS AND USE THEREOF IN MINERAL ORE PURIFICATION METHODS | KEMIRA OYJ (FI) | 2019-07-18 | — | — | US | claimed |
| EP-1846477-B1 | POLYMER DISPERSION AND PROCESS FOR PREPARING A POLYMER DISPERSION | KEMIRA OYJ (FI) | 2016-03-09 | — | — | EP | claimed |
| US-8299183-B2 | Polymer dispersion and process for preparing a polymer dispersion | AKZO NOBEL N.V. (NL) | 2012-10-30 | — | — | US | claimed |
| US-7968083-B2 | Methods of manufacturing deodorants, and deodorants resulting thereof | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2011-06-28 | — | — | US | claimed |
| EP-1846477-A1 | POLYMER DISPERSION AND PROCESS FOR PREPARING A POLYMER DISPERSION | Akzo Nobel N.V. (NL) | 2007-10-24 | — | — | EP | claimed |
| WO-2006071181-A1 | POLYMER DISPERSION AND PROCESS FOR PREPARING A POLYMER DISPERSION | AKZO NOBEL N.V. (NL) | 2006-07-06 | — | — | WO | claimed |
| US-20060142464-A1 | Polymer dispersion and process for preparing a polymer dispersion | AKZO NOBEL N.V. (NL) | 2006-06-29 | — | — | US | claimed |
| US-20050232880-A1 | Methods of manufacturing deodorants, and deodorants resulting thereof | HONG KONG POLYTECHNIC UNIVERSITY, THE (CN) | 2005-10-20 | — | — | US | claimed |
| US-6001549-A | IMAGING ELEMENT CONTAINING ANTISTATIC AGENT | EASTMAN KODAK COMPANY (US) | 1999-12-14 | — | — | US | claimed |
| WO-2024089994-A1 | WATER DROPLET-IN-OIL EMULSION PAPER STRENGTH ENHANCER | ハイモ株式会社 | 2024-05-02 | — | — | WO | disclosed |
| US-20240052116-A1 | ELECTROLYSIS USING MEMBRANE WITH ACRYLAMIDE MOIETY | Dioxycle (FR) | 2024-02-15 | — | — | US | disclosed |
| US-20240043594-A1 | POLYMERS AND MEMBRANES WITH ACRYLAMIDE MOIETY | Dioxycle (FR) | 2024-02-08 | — | — | US | disclosed |
| US-11891468-B1 | Polymers and membranes with acrylamide moiety | Dioxycle (FR) | 2024-02-06 | — | — | US | disclosed |
| US-4340655-A | Thermal and mechanical barrier layers for optical recording elements | EASTMAN KODAK COMPANY (US) | 1982-07-20 | — | — | US | disclosed |
| EP-0042307-A2 | An optical recording element and a method of recording information using the element | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1981-12-23 | — | — | EP | disclosed |
| EP-0032905-A4 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS. | FOLEY WILLIAM M JUN | 1981-08-27 | — | — | EP | disclosed |
| EP-0032905-A1 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS | FOLEY, Jr., William M. (US) | 1981-08-05 | — | — | EP | disclosed |
| WO-1980002840-A1 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS | FOLEY W | 1980-12-24 | — | — | WO | disclosed |