Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 10/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 9/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 9/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31476923 | 0.93 | BCHE (0.51) | BCHEACHEPLAAT5PLAAT4ALDH1A1 | |
| Sulfuric Acid SCHEMBL6476044 | 0.93 | PLAAT5 (0.43) | BCHEACHEPLAAT5PLAAT4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4884176 | 0.92 | BCHE (0.53) | BCHEACHEPLAAT5PLAAT4ALDH1A1 | |
| SCHEMBL17555032 | 0.85 | DNM1 (0.48) | BCHEACHEPLAAT5PLAAT4ALDH1A1 | |
| Bromide SCHEMBL29825165 | 0.84 | DNM1 (0.49) | BCHEACHEPLAAT5PLAAT4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1840256 | 0.84 | KMT2A (0.49) | BCHEACHEPLAAT5PLAAT4ALDH1A1 | |
| Sulfuric Acid SCHEMBL6473405 | 0.82 | TGM2 (0.44) | BCHEACHEALDH1A1SMN1; SMN2DNM1 | |
| SCHEMBL9540491 | 0.79 | BCHE (0.49) | BCHEACHEALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18314761 | 0.78 | BCHE (0.40) | BCHEACHEPLAAT5PLAAT4ALDH1A1 | |
| Sulfuric Acid SCHEMBL2790955 | 0.77 | MEN1 (0.40) | BCHEACHEALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005075531-A1 | AMPHIPHILIC BLOCK AND GRAFT COPOLYMERS CONTAINING HEAVY ELEMENTS, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS X-RAY CONTRAST AGENTS | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2005-08-18 | — | — | WO | disclosed |