Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.53 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.38 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 7/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 7/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 6/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31476923 | 0.99 | BCHE (0.51) | BCHEACHESMN1; SMN2ALDH1A1NPC1 | |
| Sulfuric Acid SCHEMBL6472910 | 0.92 | BCHE (0.46) | BCHEACHESMN1; SMN2ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL1840256 | 0.92 | KMT2A (0.49) | BCHEACHESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL17555032 | 0.90 | DNM1 (0.48) | BCHEACHESMN1; SMN2ALDH1A1NPC1 | |
| Bromide SCHEMBL29825165 | 0.89 | DNM1 (0.49) | BCHEACHESMN1; SMN2ALDH1A1NPC1 | |
| Sulfuric Acid SCHEMBL6476044 | 0.84 | PLAAT5 (0.43) | BCHEACHESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9540491 | 0.83 | BCHE (0.49) | BCHEACHESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL18314761 | 0.82 | BCHE (0.40) | BCHEACHESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL18314766 | 0.81 | PSMD14 (0.40) | BCHEACHESMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28671813 | 0.80 | TGM2 (0.48) | BCHEACHESMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4361187-A1 | VISCOSITY INDEX IMPROVER, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATORS | Sanyo Chemical Industries, Ltd. (JP) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022270342-A1 | VISCOSITY INDEX IMPROVER, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATORS | 三洋化成工業株式会社 | 2022-12-29 | — | — | WO | disclosed |
| EP-3075748-B1 | METHOD FOR PRODUCING POLYMERS WITH RADICAL POLYMERIZATION INITIATOR | ZEON CORP (JP) | 2020-11-18 | — | — | EP | disclosed |
| US-10689336-B2 | Radical polymerization initiator and method for producing polymers | ZEON CORPORATION (JP) | 2020-06-23 | — | — | US | disclosed |
| US-20190292146-A1 | RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS | KYOTO UNIVERSITY (JP) | 2019-09-26 | — | — | US | disclosed |
| EP-3070138-B1 | ULTRAVIOLET SCATTERING AGENT AND APPLICATION THEREFOR | NISSHINBO HOLDINGS INC (JP) | 2019-01-02 | — | — | EP | disclosed |
| US-20160297755-A1 | RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS | ZEON CORPORATION (JP) | 2016-10-13 | — | — | US | disclosed |
| EP-3075748-A1 | RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS | Zeon Corporation (JP) | 2016-10-05 | — | — | EP | disclosed |
| EP-3070138-A1 | ULTRAVIOLET SCATTERING AGENT AND APPLICATION THEREFOR | Nisshinbo Holdings Inc. (JP) | 2016-09-21 | — | — | EP | disclosed |
| US-20160262988-A1 | ULTRAVIOLET SCATTERING AGENT AND APPLICATION THEREFOR | NISSHINBO HOLDINGS, INC. (JP) | 2016-09-15 | — | — | US | disclosed |
| US-9093196-B2 | Conductive particles and method of preparing the same | NISSHINBO HOLDINGS, INC. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-20080078977-A1 | CONDUCTIVE PARTICLES AND METHOD OF PREPARING THE SAME | NISSHINBO INDUSTRIES, INC. (JP) | 2008-04-03 | — | — | US | disclosed |
| US-20070142595-A1 | Oval-spherical organic polymer particle and process for producing the same | NISSHINBO INDUSTRIES, INC. (JP) | 2007-06-21 | — | — | US | disclosed |
| US-20070054123-A1 | Oval-spherical organic polymer particles and method of production | NISSHINBO INDUSTRIES, INC. (JP) | 2007-03-08 | — | — | US | disclosed |
| EP-1721911-A1 | OVAL-SPHERICAL ORGANIC POLYMER PARTICLE AND PROCESS FOR PRODUCING THE SAME | Nisshinbo Industries, Inc. (JP) | 2006-11-15 | — | — | EP | disclosed |
| US-20040062989-A1 | Binding agent for electrode of electrochemical element and electrode | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689336-B2 | Radical polymerization initiator and method for producing polymers | PRMT1, ROS1, TERB1 | ACHE 2014/4885CHRM2 618/4885CHRM1 121/4885 |
| US-20160297755-A1 | RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS | PRMT1, ROS1, TERB1 | ACHE 2014/4885CHRM2 618/4885CHRM1 121/4885 |
| US-20190292146-A1 | RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS | PRMT1, ROS1, TERB1 | ACHE 2014/4885CHRM2 618/4885CHRM1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.