Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15624412 | 0.76 | TRPV1 (0.47) | EPHX2TRPV1 | |
| SCHEMBL31608519 | 0.74 | EPHX2 (0.44) | EPHX2SLC40A1NFE2L2HSD11B1MEN1 | |
| SCHEMBL31009386 | 0.74 | EPHX2 (0.44) | EPHX2NFE2L2HSD11B1MEN1TNF | |
| SCHEMBL610024 | 0.74 | EPHX2 (0.44) | EPHX2NFE2L2HSD11B1MEN1TNF | |
| SCHEMBL8436654 | 0.74 | EPHX2 (0.44) | EPHX2SLC40A1NFE2L2HSD11B1MEN1 | |
| SCHEMBL2305693 | 0.73 | EPHX2 (0.43) | EPHX2SLC40A1SLC22A12NFE2L2HSD11B1 | |
| SCHEMBL162911 | 0.73 | EPHX2 (0.43) | EPHX2NFE2L2HSD11B1MEN1TNF | |
| SCHEMBL120643 | 0.73 | RPS6KA5 (0.45) | EPHX2NFE2L2HSD11B1MEN1TNF | |
| SCHEMBL6966993 | 0.73 | EPHX2 (0.43) | EPHX2SLC40A1NFE2L2HSD11B1MEN1 | |
| SCHEMBL1313342 | 0.73 | EPHX2 (0.47) | EPHX2NFE2L2HSD11B1MEN1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210061764-A1 | BIVALENT LINKERS AND CONJUGATES THEREOF | ENDOCYTE INC (US) | 2021-03-04 | — | — | US | disclosed |
| US-10647676-B2 | Bivalent linkers and conjugates thereof | ENDOCYTE, INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190300482-A1 | BIVALENT LINKERS AND CONJUGATES THEREOF | ENDOCYTE INC (US) | 2019-10-03 | — | — | US | disclosed |
| US-20190100494-A1 | BIVALENT LINKERS AND CONJUGATES THEROF | ENDOCYTE INC (US) | 2019-04-04 | — | — | US | disclosed |
| US-20170320826-A1 | BIVALENT LINKERS AND CONJUGATES THEREOF | ENDOCYTE INC (US) | 2017-11-09 | — | — | US | disclosed |
| US-9550734-B2 | Bivalent linkers and conjugates thereof | ENDOCYTE, INC. (US) | 2017-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190100494-A1 | BIVALENT LINKERS AND CONJUGATES THEROF | PAICS, MTHFD2, BTD | EPHX2 66/4885SLC40A1 216/4885SLC22A12 764/4885 |
| US-10647676-B2 | Bivalent linkers and conjugates thereof | VDR, ERBB2, FOLR1 | EPHX2 41/4885SLC40A1 235/4885SLC22A12 371/4885 |
| US-20210061764-A1 | BIVALENT LINKERS AND CONJUGATES THEREOF | PAICS, FOLR2, DCLRE1A | EPHX2 31/4885SLC40A1 236/4885SLC22A12 676/4885 |
| US-20190300482-A1 | BIVALENT LINKERS AND CONJUGATES THEREOF | PAICS, FOLR2, DCLRE1A | EPHX2 31/4885SLC40A1 236/4885SLC22A12 676/4885 |
| US-20170320826-A1 | BIVALENT LINKERS AND CONJUGATES THEREOF | PAICS, FOLR2, DCLRE1A | EPHX2 31/4885SLC40A1 236/4885SLC22A12 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.