Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 13/20 | 0.58 |
| ▸ | CA1 | P00915 | 10/20 | 0.58 |
| ▸ | CA9 | Q16790 | 9/20 | 0.58 |
| ▸ | CA12 | O43570 | 6/20 | 0.58 |
| ▸ | CA5A | P35218 | 5/20 | 0.58 |
| ▸ | CA6 | P23280 | 4/20 | 0.58 |
| ▸ | CA4 | P22748 | 4/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29965023 | 1.00 | CDK2 (0.61) | CDK2CA2CA1CA9CA12 | |
| SCHEMBL11168990 | 0.91 | CDK2 (0.53) | CDK2CA2CA1CA9CA12 | |
| SCHEMBL202947 | 0.83 | CA2 (0.70) | CDK2CA2CA1CA9CA12 | |
| SCHEMBL28882144 | 0.81 | STAT3 (0.56) | CDK2CA2CA1CA9CA12 | |
| SCHEMBL29381412 | 0.81 | TDP1 (0.50) | CDK2CA2CA1CA9CA12 | |
| SCHEMBL190005 | 0.81 | TDP1 (0.50) | CDK2CA2CA1CA9CA12 | |
| SCHEMBL18837 | 0.81 | TDP1 (0.50) | CDK2CA2CA1CA9CA12 | |
| SCHEMBL11149914 | 0.81 | CA2 (0.47) | CDK2CA2CA1CA9CA12 | |
| SCHEMBL10749655 | 0.80 | CA2 (0.67) | CDK2CA2CA1CA9CA12 | |
| SCHEMBL10750176 | 0.80 | CA2 (0.67) | CDK2CA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022096-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | GENECODE (EE) | 2026-01-22 | — | — | US | claimed |
| WO-2021101927-A1 | WDR5-MYC INHIBITORS | VANDERBILT UNIVERSITY (US) | 2021-05-27 | — | — | WO | claimed |
| CN-110642791-A | Sulfonylurea compound, preparation method thereof and application thereof in preparing herbicide | 南开大学 | 2020-01-03 | — | — | CN | claimed |
| EP-2504003-A1 | NITROXYL DONORS FOR THE TREATMENT OF PULMONARY HYPERTENSION | Cardioxyl Pharmaceuticals Inc. (US) | 2012-10-03 | — | — | EP | claimed |
| WO-2011063400-A1 | NITROXYL DONORS FOR THE TREATMENT OF PULMONARY HYPERTENSION | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2011-05-26 | — | — | WO | claimed |
| WO-2011063339-A1 | NITROXYL DONORS FOR THE TREATMENT OF PULMONARY HYPERTENSION | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2011-05-26 | — | — | WO | claimed |
| EP-1998761-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS | Johns Hopkins University School of Medicine (US) | 2008-12-10 | — | — | EP | claimed |
| CN-100439329-C | 5-Amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing them and intermediates for their preparation | KISSEI PHARMACEUTICAL (JP) | 2008-12-03 | — | — | CN | claimed |
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | claimed |
| WO-2007109175-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2007-09-27 | — | — | WO | claimed |
| US-20050154231-A1 | Tamsulosin derivative | RANBAXY LABORATORIES LIMITED (IN) | 2005-07-14 | — | — | US | claimed |
| EP-1501793-A1 | TAMSULOSIN DERIVATIVE | RANBAXY LABORATORIES, LTD. (IN) | 2005-02-02 | — | — | EP | claimed |
| EP-1436371-A2 | ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING | Call, Krimhild (DE) | 2004-07-14 | — | — | EP | claimed |
| US-6727359-B2 | REACTING PHENOXIDE SULFONYLCHLORIDE AND ACETOACETAMIDE-N-SULFONYL PHENOXIDE AND AMMONIA USING CATALYST | BDL CORPORATION | 2004-04-27 | — | — | US | claimed |
| CN-1468215-A | 5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the same and intermediates for their preparation | ����ҩƷ��ҵ��ʽ���� | 2004-01-14 | — | — | CN | claimed |
| WO-2003093227-A1 | TAMSULOSIN DERIVATIVE | RANBAXY LABORATORIES LIMITED (IN) | 2003-11-13 | — | — | WO | claimed |
| US-20030065172-A1 | Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor | BDL CORPORATION | 2003-04-03 | — | — | US | claimed |
| WO-2002099023-A2 | ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING | CALL, KRIMHILD (DE) | 2002-12-12 | — | — | WO | claimed |
| EP-0044807-B1 | N-PHENYLSULFONYL-N'-PYRIMIDINYL- AND -TRIAZINYL UREAS | CIBA-GEIGY AG (CH) | 1985-11-21 | — | — | EP | claimed |
| EP-0044212-A1 | Herbicidal o-alkylsulfonyloxy- and o-alkylsulfonylamino-benzenesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154231-A1 | Tamsulosin derivative | ADRB1, ADRA1B, ADRA2B | CDK2 3942/4885CA2 3014/4885CA1 4270/4885 |
| US-20030065172-A1 | Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor | PDXK, ITK, KHK | CDK2 198/4885CA2 1215/4885CA1 2380/4885 |
| US-20260022096-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | CNR1, CDR2, SMN1; SMN2 | CDK2 2161/4885CA2 240/4885CA1 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.