Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.67 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | BRD1 | O95696 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434849 | 0.83 | SLC40A1 (0.60) | SLC40A1TDP1 | |
| SCHEMBL18434448 | 0.82 | SLC40A1 (0.61) | SLC40A1TDP1 | |
| SCHEMBL18434504 | 0.80 | SLC40A1 (0.62) | SLC40A1 | |
| SCHEMBL18434621 | 0.80 | SLC40A1 (0.65) | SLC40A1SIRT6BRD1TAF1BRPF1 | |
| SCHEMBL11973086 | 0.80 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434855 | 0.76 | SLC40A1 (0.62) | SLC40A1TDP1 | |
| SCHEMBL18434500 | 0.75 | SLC40A1 (0.63) | SLC40A1 | |
| SCHEMBL18434824 | 0.75 | SLC40A1 (0.63) | SLC40A1DRD2 | |
| SCHEMBL18434714 | 0.71 | SLC40A1 (0.66) | SLC40A1 | |
| SCHEMBL18434697 | 0.71 | SLC40A1 (0.67) | SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |