Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434582 | 0.67 | SLC40A1 (0.43) | SLC40A1L3MBTL1KDM4EMPIMEN1 | |
| SCHEMBL16955677 | 0.66 | ALDH1A1 (0.39) | ALDH1A1MAPTPKMTDP1 | |
| SCHEMBL19627551 | 0.64 | ALDH1A1 (0.39) | L3MBTL1KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL8856164 | 0.64 | HSP90AA1 (0.42) | L3MBTL1KDM4EMPIMEN1ALDH1A1 | |
| SCHEMBL22923964 | 0.62 | KDM4E (0.55) | L3MBTL1KDM4EMPIMEN1ALDH1A1 | |
| SCHEMBL1007795 | 0.61 | DHFR (0.39) | L3MBTL1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL7743581 | 0.61 | L3MBTL1 (0.50) | SLC40A1L3MBTL1KDM4EMPIMEN1 | |
| SCHEMBL22288159 | 0.61 | HSP90AA1 (0.48) | L3MBTL1KDM4EMPIMEN1ALDH1A1 | |
| SCHEMBL29661831 | 0.61 | HSP90AA1 (0.48) | L3MBTL1KDM4EMPIMEN1ALDH1A1 | |
| SCHEMBL7314285 | 0.60 | ALDH1A1 (0.43) | ALDH1A1MAPTPKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |