Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154699 | 0.74 | TPSAB1 (0.48) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL3337090 | 0.72 | ITGB1 (0.68) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL11499414 | 0.71 | ALDH1A1 (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL1273314 | 0.71 | CHRM2 (0.50) | POLB | |
| SCHEMBL18447471 | 0.70 | ITGB1 (0.38) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL5837860 | 0.70 | L3MBTL1 (0.58) | KDM4ETSHRL3MBTL1POLB | |
| SCHEMBL27552925 | 0.70 | HTT (0.59) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL1240108 | 0.69 | KDM4E (0.54) | ALDH1A1KDM4ETSHR | |
| SCHEMBL12918110 | 0.69 | CHRNB2 (0.44) | — | |
| SCHEMBL27338294 | 0.69 | SMN1; SMN2 (0.55) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11178873-B2 | Cyclic N-carboxamide compounds useful as herbicides | FMC CORPORATION (US) | 2021-11-23 | — | — | US | claimed |
| US-10653148-B2 | — | — | 2020-05-19 | — | — | US | claimed |
| US-20180213788-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | FMC CORPORATION | 2018-08-02 | — | — | US | claimed |
| EP-3328836-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-06-06 | — | — | EP | claimed |
| WO-2017023515-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-02-09 | — | — | WO | claimed |
| CN-108137512-B | Cyclic N-amide compounds useful as herbicides | FMC公司 | 2022-05-31 | — | — | CN | disclosed |
| US-11178873-B2 | Cyclic N-carboxamide compounds useful as herbicides | FMC CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-10653148-B2 | — | — | 2020-05-19 | — | — | US | disclosed |
| US-20180213788-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | FMC CORPORATION | 2018-08-02 | — | — | US | disclosed |
| EP-3328836-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017023515-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10653148-B2 | — | CYP1B1, CYP1A1, C5 | SMN1; SMN2 4235/4885TP53 1608/4885NPC1 1365/4885 |
| US-11178873-B2 | Cyclic N-carboxamide compounds useful as herbicides | CHRM2, NIT2, CHRM1 | SMN1; SMN2 3839/4885TP53 3134/4885NPC1 4244/4885 |
| US-20180213788-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | CHRM2, NIT2, CHRM1 | SMN1; SMN2 3839/4885TP53 3134/4885NPC1 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.