Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5001090 | 0.94 | TOP1 (0.40) | MAPK14CYP17A1CA12CA1CA9 | |
| SCHEMBL5000911 | 0.94 | TOP1 (0.40) | MAPK14CYP17A1CA12CA1CA9 | |
| SCHEMBL15385155 | 0.94 | TOP1 (0.40) | MAPK14CYP17A1CA12CA1CA9 | |
| SCHEMBL14878099 | 0.87 | CCNC (0.39) | MAPK14CYP17A1CA12CA1CA9 | |
| SCHEMBL6429116 | 0.87 | MAPK14 (0.38) | MAPK14CYP17A1CA12CA1CA9 | |
| SCHEMBL2392134 | 0.87 | HDAC3 (0.39) | MAPK14CYP17A1CA12CA1CA9 | |
| SCHEMBL14099783 | 0.86 | DAO (0.37) | MAPK14PRKDCP2RY14ACHEBACE1 | |
| SCHEMBL6429813 | 0.85 | MAPK14 (0.40) | MAPK14CYP17A1CA12CA1CA9 | |
| SCHEMBL19739304 | 0.85 | CYP17A1 (0.44) | MAPK14CYP17A1HDAC3HDAC1HDAC6 | |
| SCHEMBL13879751 | 0.85 | P2RY12 (0.38) | PRKDCP2RY14DRD2ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970720-B | Aurora A protein inhibitor and preparation method and pharmaceutical application thereof | 深圳先进技术研究院 | 2020-07-03 | — | — | CN | claimed |
| CN-106674209-B | Programmed death receptor 1 gene inhibitor and preparation method and application thereof | 深圳先进技术研究院 | 2020-03-06 | — | — | CN | claimed |
| CN-122036924-A | Synthetic method of bionic collagen hexapeptide | 成都欣肽生物科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-122011119-A | Preparation method and application of bionic collagen cyclohexapeptide | 成都欣肽生物科技有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-12583857-B2 | Anti-liferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | PHEON THERAPEUTICS LTD (GB) | 2026-03-24 | — | — | US | disclosed |
| US-20250368628-A1 | METHODS AND COMPOUNDS FOR MODULATING INHERITED GENETIC DISEASES | DESIGN THERAPEUTICS INC (US) | 2025-12-04 | — | — | US | disclosed |
| US-20250340567-A1 | Next Generation Synthetic Transcription Factors | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-11-06 | — | — | US | disclosed |
| US-12454526-B2 | Method for producing pyrrole-imidazole (poly)amide | KANEKA CORPORATION (JP) | 2025-10-28 | — | — | US | disclosed |
| EP-4633738-A1 | CYTOTOXIC COMPOUNDS | Pheon Therapeutics Ltd (GB) | 2025-10-22 | — | — | EP | disclosed |
| WO-2025122764-A1 | METHODS AND COMPOUNDS FOR MODULATING INHERITED GENETIC DISEASES | Design Therapeutics, Inc. (US) | 2025-06-12 | — | — | WO | disclosed |
| EP-4539839-A1 | METHODS AND COMPOUNDS FOR MODULATING INHERITED GENETIC DISEASES | Design Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2002000650-A2 | NOVEL COMPOUNDS POSSESSING ANTIBACTERIAL, ANTIFUNGAL OR ANTITUMOR ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2002-01-03 | — | — | WO | disclosed |
| US-6303312-B1 | MODIFYING CELL PHENOTYPE; MEDICAL RESEARCH AND THERAPY | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2001-10-16 | — | — | US | disclosed |
| US-6143901-A | FORMINGA SPECIFIC COMPLEX BETWEEN A TARGET SEQUENCE OF DOUBLE STRANDED DNA AND AN OLIGOMER OR POLYMER OF N-METHYLPYRROLE CARBOXAMIDE AND N-METHYLIMIDAZOLE CARBOXAMID WHEREIN N-HETEROCYLCES ARE CONNCETED WITH AN AMINO ACID LINKING GROUP | GENESOFT, INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6090947-A | Method for the synthesis of pyrrole and imidazole carboxamides on a solid support | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0986539-A1 | DNA-BINDING PYRROLE AND IMIDAZOLE POLYAMIDE DERIVATIVES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-03-22 | — | — | EP | disclosed |
| US-5998140-A | COMPLEXES OF CELL WITH OLIGOMER | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-12-07 | — | — | US | disclosed |
| WO-1998049142-A1 | DNA-BINDING PYRROLE AND IMIDAZOLE POLYAMIDE DERIVATIVES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0819133-A2 | COVALENTLY LINKED OLIGONUCLEOTIDE MINOR GROOVE BINDER CONJUGATES | EPOCH PHARMACEUTICALS, INC. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996032496-A2 | COVALENTLY LINKED OLIGONUCLEOTIDE MINOR GROOVE BINDER CONJUGATES | MICROPROBE CORPORATION (US) | 1996-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583857-B2 | Anti-liferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | CNR1, MTNR1B, MTNR1A | MAPK14 1957/4885CYP17A1 1059/4885CA12 2663/4885 |
| US-20250368628-A1 | METHODS AND COMPOUNDS FOR MODULATING INHERITED GENETIC DISEASES | CLN6, GATAD2B, MITF | MAPK14 4036/4885CYP17A1 3776/4885CA12 4783/4885 |
| US-20250340567-A1 | Next Generation Synthetic Transcription Factors | ZFX, RUNX1, JUN | MAPK14 3533/4885CYP17A1 2479/4885CA12 3924/4885 |
| US-12454526-B2 | Method for producing pyrrole-imidazole (poly)amide | DDC, PAM, AADAC | MAPK14 3034/4885CYP17A1 3552/4885CA12 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.