Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18106220 | 0.92 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2ZDHHC20ZDHHC2 | |
| SCHEMBL15617163 | 0.92 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2ZDHHC20ZDHHC2 | |
| SCHEMBL19620229 | 0.86 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2ZDHHC20ZDHHC2 | |
| SCHEMBL49389 | 0.85 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2TSHRZDHHC20ZDHHC2 | |
| SCHEMBL20274451 | 0.85 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL18458050 | 0.82 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2TSHRZDHHC20ZDHHC2 | |
| SCHEMBL19493415 | 0.82 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2ZDHHC20ZDHHC2 | |
| SCHEMBL9861082 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2ZDHHC20ZDHHC2 | |
| SCHEMBL21652434 | 0.79 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TSHRZDHHC20ZDHHC2 | |
| SCHEMBL18734536 | 0.79 | ZDHHC20 (0.41) | ALDH1A1TSHRZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11116702-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-20200022884-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2020-01-23 | — | — | US | disclosed |
| WO-2019173656-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2019-09-12 | — | — | WO | disclosed |
| WO-2018108948-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2018-06-21 | — | — | WO | disclosed |
| EP-3335689-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GmbH (DE) | 2018-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11116702-B2 | Dental composition | MTR, CAD, PAM | ALDH1A1 1171/4885SMN1; SMN2 4239/4885TSHR 4367/4885 |
| US-20200022884-A1 | DENTAL COMPOSITION | MTR, CAD, PAM | ALDH1A1 1171/4885SMN1; SMN2 4239/4885TSHR 4367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.