Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862821 | 0.82 | COMT (0.40) | ENPP1MAPTLMNAMEN1USP2 | |
| SCHEMBL20806202 | 0.80 | COMT (0.39) | ENPP1MAPTLMNAMEN1USP2 | |
| SCHEMBL18462105 | 0.78 | HSD11B1 (0.40) | MAPTMEN1USP2GAATSHR | |
| SCHEMBL18464326 | 0.77 | NPC1 (0.43) | MAPTLMNAMEN1USP2GAA | |
| SCHEMBL2602433 | 0.76 | MAPT (0.51) | ENPP1MAPTLMNAMEN1USP2 | |
| SCHEMBL13958188 | 0.75 | LMNA (0.42) | ENPP1MAPTLMNAMEN1USP2 | |
| SCHEMBL1108699 | 0.75 | LMNA (0.39) | ENPP1MAPTLMNAMEN1USP2 | |
| SCHEMBL11887463 | 0.72 | HSD17B1 (0.38) | MAPTLMNAMEN1USP2GAA | |
| SCHEMBL862603 | 0.72 | SENP1 (0.35) | MAPTLMNAMEN1USP2GAA | |
| Ammonia Solution, Strong SCHEMBL18507939 | 0.72 | TDP1 (0.44) | ENPP1MAPTLMNAMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017019964-A1 | GRAPHITIC COMPOUNDS AND METHODS OF MAKING AND USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-02-02 | — | — | WO | disclosed |