Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | CASP6 | P55212 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18698222 | 0.80 | SIGMAR1 (0.37) | PRKCISIGMAR1GAAALDH1A1MAPT | |
| SCHEMBL9706128 | 0.78 | HPGD (0.41) | GAAALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL13879940 | 0.76 | SIGMAR1 (0.37) | SIGMAR1GAAALDH1A1MAPTKDM4E | |
| SCHEMBL13689913 | 0.76 | HTT (0.36) | GAAALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL18077360 | 0.76 | KDM4E (0.49) | GAAALDH1A1MAPTKDM4EGLA | |
| SCHEMBL8995959 | 0.74 | ALDH1A1 (0.59) | PRKCIGAAALDH1A1MAPTKDM4E | |
| SCHEMBL12990358 | 0.73 | CYP3A4 (0.36) | GAAALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL8033091 | 0.73 | PRKCI (0.41) | PRKCISIGMAR1GAAALDH1A1MAPT | |
| SCHEMBL10314645 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KDM4ETDP1SMN1; SMN2HSD17B10 | |
| SCHEMBL27890267 | 0.73 | KMT2A (0.36) | SIGMAR1ALDH1A1MAPTKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190125882-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2019-05-02 | — | — | US | disclosed |
| US-10179175-B2 | Isatoic anhydride derivatives and applications thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180110862-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2018-04-26 | — | — | US | disclosed |
| US-9867883-B2 | Isatoic anhydride derivatives and applications thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2018-01-16 | — | — | US | disclosed |
| US-20170035893-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179175-B2 | Isatoic anhydride derivatives and applications thereof | AASDHPPT, CA13, CA12 | PRKCI 1003/4885SIGMAR1 4041/4885GAA 54/4885 |
| US-20190125882-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | AASDHPPT, CA13, CA12 | PRKCI 1003/4885SIGMAR1 4041/4885GAA 54/4885 |
| US-20180110862-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | AASDHPPT, CA13, CA12 | PRKCI 1003/4885SIGMAR1 4041/4885GAA 54/4885 |
| US-20170035893-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | AASDHPPT, CA13, CA12 | PRKCI 1003/4885SIGMAR1 4041/4885GAA 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.