Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | SLC26A3 | P40879 | 5/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198348 | 0.97 | MAOB (0.40) | MAOBMTNR1AMTNR1BSLC26A3HTR2B | |
| SCHEMBL1858690 | 0.84 | GPR52 (0.48) | MTNR1AMTNR1BGPR52KMT2A | |
| SCHEMBL1849327 | 0.82 | MTNR1A (0.46) | MAOBMTNR1AMTNR1BHTR2BGPR52 | |
| SCHEMBL1848567 | 0.77 | ALOX5 (0.56) | MAOBMTNR1AMTNR1BSLC26A3HTR2B | |
| Bromide SCHEMBL1852155 | 0.75 | ALOX5 (0.54) | MAOBMTNR1AMTNR1BSLC26A3HTR2B | |
| SCHEMBL1858526 | 0.75 | MAPT (0.39) | HTR2BABHD6MAPTKMT2ATDP1 | |
| SCHEMBL1852157 | 0.73 | ALOX5 (0.52) | MAOBMTNR1AMTNR1BSLC26A3HTR2B | |
| SCHEMBL1854575 | 0.71 | HTR2B (0.42) | HTR2BMAPTKMT2ATDP1 | |
| SCHEMBL1852178 | 0.70 | GPR52 (0.56) | MTNR1AMTNR1BGPR52 | |
| SCHEMBL27611980 | 0.69 | EDNRA (0.64) | EDNRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |