Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.45 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503610 | 0.92 | LMNA (0.40) | KCNQ3KCNQ2KCNE1KCNQ1LMNA | |
| SCHEMBL18503634 | 0.91 | LMNA (0.40) | KCNQ3KCNQ2KCNE1KCNQ1KIF11 | |
| SCHEMBL16771948 | 0.91 | AKR1C3 (0.41) | KCNQ3KCNQ2KCNE1KCNQ1LMNA | |
| SCHEMBL18503594 | 0.90 | KIF11 (0.41) | KIF11LMNACHRM3TP53GAA | |
| SCHEMBL18503593 | 0.89 | P2RX7 (0.41) | KIF11LMNACHRM3TP53GAA | |
| SCHEMBL18503628 | 0.87 | HDAC6 (0.42) | KCNQ3KCNQ2KCNE1KCNQ1KIF11 | |
| SCHEMBL19566549 | 0.86 | P2RX7 (0.47) | KIF11LMNACHRM3TP53GAA | |
| SCHEMBL18503597 | 0.85 | POLB (0.42) | KIF11TP53CYP11B2CYP11B1PTGES | |
| SCHEMBL18503599 | 0.85 | TP53 (0.39) | KIF11LMNACHRM3TP53GAA | |
| SCHEMBL18503595 | 0.85 | CYP11B2 (0.42) | LMNACHRM3TP53GAAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | ACHE, DDT, DNPH1 | KCNQ3 237/4885KCNQ2 144/4885KCNE1 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.