Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 5/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503594 | 0.90 | KIF11 (0.41) | LMNAGAATP53PTGESHDAC3 | |
| SCHEMBL18503614 | 0.86 | LMNA (0.41) | LMNAGAATP53PTGESKCNK3 | |
| SCHEMBL19566558 | 0.86 | TP53 (0.48) | LMNAGAATP53HDAC3HDAC1 | |
| SCHEMBL16760327 | 0.84 | P2RX7 (0.40) | LMNAGAATP53PTGESP2RX7 | |
| SCHEMBL18503619 | 0.84 | TP53 (0.45) | LMNAGAATP53PTGESKCNK3 | |
| SCHEMBL17917768 | 0.83 | P2RX7 (0.39) | LMNAGAATP53PTGESP2RX7 | |
| SCHEMBL18503623 | 0.81 | KCNH2 (0.43) | TP53PTGESP2RX7KCNK3KCNK9 | |
| SCHEMBL18503593 | 0.80 | P2RX7 (0.41) | LMNAGAATP53P2RX7CHRM3 | |
| SCHEMBL18503606 | 0.80 | KCNQ3 (0.45) | LMNAGAATP53PTGESHDAC3 | |
| SCHEMBL18503634 | 0.78 | LMNA (0.40) | LMNAGAATP53PTGESHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | ACHE, DDT, DNPH1 | LMNA 2055/4885GAA 1213/4885TP53 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.