Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.66 |
| ▸ | CTSB | P07858 | 1/20 | 0.66 |
| ▸ | JUN | P05412 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.62 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.62 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.62 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598355 | 0.90 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2ACAPN1 | |
| SCHEMBL5598357 | 0.90 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2ACAPN1 | |
| SCHEMBL28360809 | 0.85 | CAPN1 (0.85) | MAPTALDH1A1MEN1KMT2ACAPN1 | |
| SCHEMBL11999773 | 0.83 | MAPT (0.85) | MAPTALDH1A1MEN1KMT2ACAPN1 | |
| SCHEMBL10468807 | 0.83 | MAPT (0.85) | MAPTALDH1A1MEN1KMT2ACAPN1 | |
| SCHEMBL10468808 | 0.83 | MAPT (0.85) | MAPTALDH1A1MEN1KMT2ACAPN1 | |
| SCHEMBL30163524 | 0.81 | ALDH1A1 (0.57) | MAPTALDH1A1MEN1KMT2ACAPN1 | |
| SCHEMBL29428462 | 0.81 | MAPT (0.82) | MAPTALDH1A1MEN1KMT2ACAPN1 | |
| SCHEMBL18508968 | 0.81 | NFKB1 (0.67) | MAPTALDH1A1MEN1KMT2ACAPN1 | |
| SCHEMBL16382581 | 0.80 | MAPT (0.78) | MAPTALDH1A1MEN1KMT2ACAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170042867-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2017-02-16 | — | — | US | disclosed |
| US-20170042866-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170042867-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, COMT | MAPT 198/4885ALDH1A1 320/4885MEN1 2595/4885 |
| US-20170042866-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, COMT | MAPT 198/4885ALDH1A1 320/4885MEN1 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.