Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | JUN | P05412 | 2/20 | 0.67 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.60 |
| ▸ | TFEB | P19484 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697176 | 0.88 | EPHX2 (0.56) | NFKB1JUNNFE2L2ALDH1A1TSHR | |
| SCHEMBL18508908 | 0.81 | MAPT (0.81) | NFKB1JUNNFE2L2ALDH1A1MAPT | |
| SCHEMBL1662997 | 0.81 | ALDH1A1 (0.70) | ALDH1A1TSHRAOX1MAPTTDP1 | |
| SCHEMBL5598598 | 0.80 | JUN (1.00) | NFKB1JUNNFE2L2TFEBALDH1A1 | |
| SCHEMBL5598600 | 0.80 | JUN (1.00) | NFKB1JUNNFE2L2TFEBALDH1A1 | |
| SCHEMBL20152991 | 0.80 | BACE1 (0.77) | NFKB1JUNNFE2L2TFEBALDH1A1 | |
| SCHEMBL18509207 | 0.77 | NFKB1 (0.69) | NFKB1JUNNFE2L2ALDH1A1TSHR | |
| SCHEMBL15111041 | 0.76 | KDM4E (0.71) | NFE2L2ALDH1A1CA2MEN1KMT2A | |
| SCHEMBL15111043 | 0.76 | KDM4E (0.71) | NFE2L2ALDH1A1CA2MEN1KMT2A | |
| SCHEMBL2743877 | 0.76 | NFKB1 (0.79) | NFKB1JUNNFE2L2ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200383958-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2020-12-10 | — | — | US | disclosed |
| US-20170216222-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2017-08-03 | — | — | US | disclosed |
| US-20170042867-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216222-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, COMT | NFKB1 1602/4885JUN 2579/4885NFE2L2 1139/4885 |
| US-20170042867-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, COMT | NFKB1 1602/4885JUN 2579/4885NFE2L2 1139/4885 |
| US-20200383958-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | NFKB1 841/4885JUN 2377/4885NFE2L2 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.