Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20194348 | 0.71 | HSD17B1 (0.33) | — | |
| SCHEMBL11831189 | 0.70 | SLC22A12 (0.37) | NR1H4ESR1ESR2 | |
| SCHEMBL20428093 | 0.69 | AXL (0.33) | — | |
| SCHEMBL23373028 | 0.69 | ADH1B (0.42) | — | |
| SCHEMBL21696535 | 0.68 | SMN1; SMN2 (0.46) | HPGD | |
| SCHEMBL11601038 | 0.68 | TDP1 (0.44) | — | |
| SCHEMBL23482035 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL15275916 | 0.65 | CES2 (0.38) | — | |
| SCHEMBL15434406 | 0.64 | MEN1 (0.52) | HPGD | |
| SCHEMBL23585808 | 0.64 | LMNA (0.47) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |