Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15681342 | 0.91 | TRPA1 (0.41) | PTGS2TUBB1PTGS1TRPA1 | |
| SCHEMBL18509967 | 0.86 | FGFR2 (0.39) | PTGS2TUBB1PTGS1ALOX5APFEN1 | |
| SCHEMBL17193138 | 0.82 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL13111384 | 0.82 | PDE3B (0.39) | PTGS2PTGS1ALOX5APFEN1 | |
| SCHEMBL12994276 | 0.81 | TUBB1 (0.45) | TUBB1TRPA1 | |
| SCHEMBL16856037 | 0.80 | PTGS2 (0.53) | PTGS2TUBB1PTGS1 | |
| SCHEMBL18251034 | 0.80 | TRPA1 (0.39) | PTGS2TUBB1PTGS1TRPA1 | |
| SCHEMBL12717337 | 0.80 | CYP17A1 (0.44) | PTGS2TUBB1PTGS1 | |
| SCHEMBL17791130 | 0.79 | CYP17A1 (0.42) | PTGS2PTGS1 | |
| SCHEMBL12716509 | 0.79 | TUBB1 (0.46) | PTGS2TUBB1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10400169-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-09-03 | — | — | US | disclosed |
| US-20180030350-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-02-01 | — | — | US | disclosed |
| US-20170044438-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044437-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044438-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | PTGS2 3667/4885TUBB1 918/4885PTGS1 2291/4885 |
| US-20180030350-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | PTGS2 3667/4885TUBB1 918/4885PTGS1 2291/4885 |
| US-10400169-B2 | Liquid-crystalline medium | VIM, COL2A1, COL1A1 | PTGS2 3667/4885TUBB1 918/4885PTGS1 2291/4885 |
| US-20170044437-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | PTGS2 3667/4885TUBB1 918/4885PTGS1 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.